SOCS1 and JAK1

  • Number of citations of the paper that reports this interaction (PMID 11133764)
  • 16
  • Data Source:
  • HPRD (in vitro)

SOCS1

JAK1

Gene Name suppressor of cytokine signaling 1 Janus kinase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: ATM AXL COMMD1 CRK CSF1 CSF1R CXCR4 CYTIP EGFR ERBB2 FLT3 FYN GHR GRB2 IFNGR1 IGF1R IL2RB INSR IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 RELA TCEB1 TCEB2 TEC TEK TIRAP TRIM8 VAV1 VAV2 69 interactors: ABL1 BRCA1 BTK CCR1 CCR5 CSF2RB CSF3R CXCR4 EIF2AK2 ELP2 ERBB2 FER FES GHR GNB2L1 GRB2 HIST3H3 IFNAR2 IFNGR1 IGF1R IL10RA IL21R IL2RB IL2RG IL3RA IL4R IL5RA IL6ST IL7R IL9R INPP5D INSR IRS1 IRS2 JAK3 JAKMIP1 MDK OSMR PDGFRA PDGFRB PIK3R1 PLA2G4A PLAUR PLCG2 PRKCZ PRMT5 PTK2B PTPN11 PTPN2 PTPN6 PTPRC RAF1 SH2B2 SHB SOCS1 SOCS3 STAM STAM2 STAT1 STAT2 STAT3 STAT5A STAT6 SYK TEC TNFRSF1A TOP1 TSHR TYK2
Entrez ID 8651 3716
HPRD ID 04669 00992
Ensembl ID ENSG00000185338 ENSG00000162434
Uniprot IDs O15524 Q4JHT5 P23458
PDB IDs 3EYG 3EYH 4E4L 4E4N 4E5W 4EHZ 4EI4 4FK6 4GS0 4I5C 4IVB 4IVC 4IVD 4K6Z 4K77 4L00 4L01
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Difference) ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
2c4  assign  b10  b3  b9  cd2  complementation  crossed  crosses  crossing  facs  gbp  guanylate  hlas  hybrids  ifn  oas  oligoadenylate  pairwise  permitted  responsiveness  restore  rounds  submitted  synthetase  u3  u4  unresponsive  unresponsiveness 
Tagcloud (Intersection) ?