GHR and SOCS2

  • Number of citations of the paper that reports this interaction (PMID 10585430)
  • 43
  • Data Source:
  • HPRD (in vitro, in vivo)

GHR

SOCS2

Gene Name growth hormone receptor suppressor of cytokine signaling 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Iron status biomarkers ( 19084217)
  • Response to taxane treatment (docetaxel) ( 23006423)
  • Systemic lupus erythematosus ( 18204098)
Protein-Protein Interactions 33 interactors: AP2A1 BTRC CISH DUSP7 GH1 GH2 GRB10 GRB2 IRS1 JAK1 JAK2 NCOA6 PIK3R1 PLCG1 PTPN1 PTPN11 PTPN13 PTPN2 PTPN3 PTPN6 PTPN9 PTPRB PTPRH SGTA SHC1 SOCS1 SOCS2 SOCS3 STAT3 STAT5A STAT5B STUB1 TYK2 12 interactors: ARFIP2 BMI1 EPOR GHR IGF1R INSR PLA2G1B PRLR PTK2 RYBP SOCS3 TPD52
Entrez ID 2690 8835
HPRD ID 02971 05490
Ensembl ID ENSG00000112964 ENSG00000120833
Uniprot IDs P10912 O14508
PDB IDs 1A22 1AXI 1HWG 1HWH 1KF9 2AEW 3HHR 2C9W 4JGH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  stat5b  step  sustaining 
abrogation  adenomas  alcoholic  ccl3  col1a2  col3a1  compromised  confirming  fibrotic  fivefold  gh  ghr  ghrld  hepatic  hyperlipidemia  livers  microscopic  mup1  nafld  proteomics  qpcr  selenbp2  socs3  steatosis  superarray  tgfbeta  threefold  tolerance  unravel 
Tagcloud (Difference) ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  stat5b  step  sustaining 
abrogation  adenomas  alcoholic  ccl3  col1a2  col3a1  compromised  confirming  fibrotic  fivefold  ghrld  hepatic  hyperlipidemia  livers  microscopic  mup1  nafld  proteomics  qpcr  selenbp2  socs3  steatosis  superarray  tgfbeta  threefold  tolerance  unravel 
Tagcloud (Intersection) ?
gh  ghr