GHR and STAT5A

  • Number of citations of the paper that reports this interaction (PMID 8702683)
  • 4
  • Data Source:
  • HPRD (in vivo)

GHR

STAT5A

Gene Name growth hormone receptor signal transducer and activator of transcription 5A
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Iron status biomarkers ( 19084217)
  • Response to taxane treatment (docetaxel) ( 23006423)
  • Systemic lupus erythematosus ( 18204098)
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 33 interactors: AP2A1 BTRC CISH DUSP7 GH1 GH2 GRB10 GRB2 IRS1 JAK1 JAK2 NCOA6 PIK3R1 PLCG1 PTPN1 PTPN11 PTPN13 PTPN2 PTPN3 PTPN6 PTPN9 PTPRB PTPRH SGTA SHC1 SOCS1 SOCS2 SOCS3 STAT3 STAT5A STAT5B STUB1 TYK2 72 interactors: AQP11 BMX BRCA1 BRCA2 BTK CBL CCR5 CD247 CEBPB CENPJ CRK CRKL CSNK2B CTLA4 CYP2C9 EGFR EP300 EPAS1 EPOR ERBB4 ESR1 ESR2 FN1 GHR GLUD1 GNB2 HELZ IL2RB IL2RG IL7R INSR JAK1 JAK2 JAK3 KIT LCK LEF1 MAGEA12 MAPK1 MAPK3 MRPS6 NARF NCOR2 NLK NMI NR3C1 PDGFRA PDGFRB POM121C POU2F1 PPIB PPP2CA PRMT1 PRTFDC1 PTPN1 PTPN11 PTPN2 RBMX SHC1 SRC STAP2 STAT1 STAT3 STAT5B SYK TCF12 TEK TSLP TXNDC11 UGT2B4 WASH2P ZNF596
Entrez ID 2690 6776
HPRD ID 02971 03301
Ensembl ID ENSG00000112964 ENSG00000126561
Uniprot IDs P10912 A8K6I5 K7EK35 P42229 Q59GY7
PDB IDs 1A22 1AXI 1HWG 1HWH 1KF9 2AEW 3HHR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  stat5b  step  sustaining 
advantaged  apor  arose  b8  ba  character  coincides  committed  derive  die  dn  epo  epor  erythropoietin  f3epor  homeotic  hox  hypothesize  naturally  normally  preexisting  shortened  subclones  switch  truncated  unexplored  uniquely 
Tagcloud (Difference) ?
becomes  ceptor  continuous  continuously  cwsv  dephosphorylation  eliminated  h7  internalization  involves  jak2  labile  lived  maintain  maximal  mg132  obligatory  ongoing  persisted  pervanadate  phosphotyrosine  proteasome  pulse  requirement  robust  step  sustaining 
advantaged  apor  arose  b8  ba  character  coincides  committed  derive  die  dn  epo  epor  erythropoietin  f3epor  homeotic  hox  hypothesize  naturally  normally  preexisting  shortened  subclones  switch  truncated  unexplored  uniquely 
Tagcloud (Intersection) ?
stat5b