SOCS1 and ITK

  • Number of citations of the paper that reports this interaction (PMID 10022833)
  • 24
  • Data Source:
  • HPRD (in vitro)

SOCS1

ITK

Gene Name suppressor of cytokine signaling 1 IL2-inducible T-cell kinase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: ATM AXL COMMD1 CRK CSF1 CSF1R CXCR4 CYTIP EGFR ERBB2 FLT3 FYN GHR GRB2 IFNGR1 IGF1R IL2RB INSR IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 RELA TCEB1 TCEB2 TEC TEK TIRAP TRIM8 VAV1 VAV2 29 interactors: BLNK BMX BTK CBL CD28 DOK1 ERBB2 ERBB3 FASLG FGFR1 FYN GRB2 HNRNPK IKBKG KHDRBS1 KPNA2 LAT LCK LCP2 PLCG1 PLCG2 PPIA SH2D2A SMAD4 SOCS1 SPRR2A SRC TGFBR1 WAS
Entrez ID 8651 3702
HPRD ID 04669 01746
Ensembl ID ENSG00000185338 ENSG00000113263
Uniprot IDs O15524 Q4JHT5 Q08881
PDB IDs 1SM2 1SNU 1SNX 2E6I 2LMJ 2YUQ 3MIY 3MJ1 3MJ2 3QGW 3QGY 3T9T 3V5J 3V5L 3V8T 3V8W 4HCT 4HCU 4HCV 4KIO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
adrenergic  ark  bind  btk  coincides  computer  databases  defects  difficult  difficulty  domains  find  homologues  homology  hypothesis  irs  overcome  ph  pleckstrin  program  programs  simple  substrate  teca  termini  transduction  trimeric  unrecognized  widely 
Tagcloud (Difference) ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  systemic  tlr  tlr3  tnfalpha  toll  urb597 
adrenergic  ark  bind  btk  coincides  computer  databases  defects  difficult  difficulty  domains  find  homologues  homology  hypothesis  irs  overcome  ph  pleckstrin  program  programs  simple  teca  termini  transduction  trimeric  unrecognized  widely 
Tagcloud (Intersection) ?
substrate