SOCS1 and VAV1

  • Number of citations of the paper that reports this interaction (PMID 10022833)
  • 24
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

SOCS1

VAV1

Gene Name suppressor of cytokine signaling 1 vav 1 guanine nucleotide exchange factor
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: ATM AXL COMMD1 CRK CSF1 CSF1R CXCR4 CYTIP EGFR ERBB2 FLT3 FYN GHR GRB2 IFNGR1 IGF1R IL2RB INSR IRS1 IRS2 ITK JAK1 JAK2 JAK3 KIT MPL NCK1 PDGFRB PIK3R1 PIK3R2 PIM2 RELA TCEB1 TCEB2 TEC TEK TIRAP TRIM8 VAV1 VAV2 77 interactors: ABL1 ACTA1 AOC3 ARHGDIA ARHGDIB BCR BLNK BTK CASP3 CBL CBLB CD19 CDC42 CRK CXCR4 DNM2 DOCK2 DOK1 EGFR EMD EPOR ERBB2 ERBB3 EZH2 FGFR1 FYN GRB2 HCK HNRNPK HRAS IL6ST INSR JAK2 JUN KHDRBS1 LAT LCK LCP2 LMNA MAPK1 MERTK MET NEK3 PAG1 PDGFRB PHAX PIK3R1 PLCG1 PRKCQ PRLR PTK2B PTPN22 PTPN6 RAC1 RACGAP1 RAF1 RHOA RHOG S100B SH3BP2 SHB SHC1 SIAH1 SIAH2 SLA SOCS1 SYK TEC TUBA1A TUBA4A TUBB TYK2 XRCC5 XRCC6 ZAP70 ZNF655 ZYX
Entrez ID 8651 7409
HPRD ID 04669 01284
Ensembl ID ENSG00000185338 ENSG00000141968
Uniprot IDs O15524 Q4JHT5 B2R8B5 P15498 Q96D37
PDB IDs 2CRH 2LCT 2MC1 2ROR 3BJI 3KY9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  silenced  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
Tagcloud (Difference) ?
1beta  acylethanolamines  administration  amide  anandamide  attenuated  central  comparison  concurrently  downstream  enhancing  faah  fatty  hippocampal  hydrolase  ifnalpha  ifngamma  ip  neuroinflammation  neuroinflammatory  oleoylethanolamide  palmitoylethanolamide  substrate  systemic  tlr  tlr3  tnfalpha  toll  urb597 
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  silenced  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
Tagcloud (Intersection) ?