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LPHN1 and DLG3
Number of citations of the paper that reports this interaction (PMID
10958799
)
9
Data Source:
HPRD
(two hybrid)
LPHN1
DLG3
Gene Name
latrophilin 1
discs, large homolog 3 (Drosophila)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Cell Junction
Axon
Growth Cone
Presynaptic Membrane
Neuron Projection
Synapse
Extracellular Space
Cytoplasm
Plasma Membrane
Tight Junction
Ionotropic Glutamate Receptor Complex
Postsynaptic Density
Basolateral Plasma Membrane
Growth Cone
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex
Neuronal Cell Body
Dendritic Shaft
Postsynaptic Membrane
Molecular Function
G-protein Coupled Receptor Activity
Protein Binding
Latrotoxin Receptor Activity
Carbohydrate Binding
Cell Adhesion Molecule Binding
Guanylate Kinase Activity
Protein Binding
Protein C-terminus Binding
Phosphatase Binding
Protein Phosphatase Binding
PDZ Domain Binding
Ubiquitin Protein Ligase Binding
Ionotropic Glutamate Receptor Binding
Biological Process
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
G-protein Coupled Receptor Signaling Pathway
Calcium-mediated Signaling Using Intracellular Calcium Source
Positive Regulation Of Synapse Maturation
Establishment Of Planar Polarity
Synaptic Transmission
Nervous System Development
Axon Guidance
Negative Regulation Of Cell Proliferation
Negative Regulation Of Phosphatase Activity
Receptor Clustering
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Nucleotide Phosphorylation
Receptor Localization To Synapse
Pathways
Axon guidance
L1CAM interactions
NrCAM interactions
Activation of Kainate Receptors upon glutamate binding
Activation of Ca-permeable Kainate Receptor
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ionotropic activity of Kainate Receptors
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Mortality among heart failure patients (
20400778
)
Protein-Protein Interactions
9 interactors:
ANKS1A
APC
CACNA1A
DLG3
DLG4
PSMA3
ROS1
SHANK1
SHANK2
40 interactors:
ABCA1
APC
ATP2B4
CACNG2
CALM1
CNKSR2
CRIPT
DLG1
DLG4
DLGAP1
DLGAP3
DLGAP4
ERBB4
EXOC4
EXOC7
GDA
GLS2
GRIK2
GRIN1
GRIN2A
GRIN2B
GRIN2C
GUCY1A2
KCNA4
KCNJ12
KCNJ2
KHDRBS1
KIF1B
LIN7A
LPHN1
LRP2
MAPK12
NLGN1
NLGN2
NLGN3
PTK2B
SCN4A
SCN5A
SEMA4C
SYNGAP1
Entrez ID
22859
1741
HPRD ID
14305
02177
Ensembl ID
ENSG00000082458
Uniprot IDs
O94910
Q59FY1
Q92796
PDB IDs
1UM7
2FE5
2I1N
Enriched GO Terms of Interacting Partners
?
Vocalization Behavior
Protein Localization To Synapse
Synapse Organization
Neuron Development
Social Behavior
Cell Development
Receptor Clustering
Neuron Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Morphogenesis
Nervous System Development
Neuromuscular Process Controlling Balance
Synapse Assembly
Cell Morphogenesis Involved In Differentiation
Receptor Localization To Synapse
Dendrite Morphogenesis
Neuron Projection Development
Generation Of Neurons
Cell Projection Morphogenesis
Dendritic Spine Morphogenesis
Cell Part Morphogenesis
Neurogenesis
Membrane Depolarization
Neuromuscular Process
Single-organism Behavior
Learning
Dendritic Spine Development
Dendrite Development
Regulation Of Signaling
Cell Morphogenesis
Dendritic Spine Organization
Anatomical Structure Development
Adult Behavior
Reflex
Cell Projection Organization
Cell Differentiation
Exploration Behavior
Synaptic Transmission
Behavior
Establishment Or Maintenance Of Apical/basal Cell Polarity
Regulation Of Ion Transport
Developmental Process
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Signaling
Cell Communication
Positive Regulation Of Membrane Potential
Learning Or Memory
Regulation Of Membrane Potential
System Development
Cognition
Membrane Depolarization
Cell-cell Signaling
Synaptic Transmission
Regulation Of Membrane Potential
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Regulation Of Ion Transmembrane Transport
Signaling
Cell Communication
Regulation Of Ion Transport
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Membrane Potential
Regulation Of Synaptic Transmission
Glutamate Receptor Signaling Pathway
Neuron-neuron Synaptic Transmission
Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Membrane Organization
Synaptic Transmission, Glutamatergic
Regulation Of Synaptic Plasticity
Regulation Of Synapse Structure Or Activity
Ion Transmembrane Transport
Regulation Of Signaling
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Receptor Clustering
Protein Localization To Synapse
Neurological System Process
Positive Regulation Of Synaptic Transmission
Regulation Of Receptor Activity
Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of Synaptic Transmission, Glutamatergic
Nervous System Development
Regulation Of Synaptic Transmission, Glutamatergic
Transmembrane Transport
Ion Transport
Neuromuscular Process
Regulation Of Respiratory Gaseous Exchange
Regulation Of Signal Transduction
Postsynaptic Membrane Organization
Learning
Regulation Of Long-term Neuronal Synaptic Plasticity
Postsynaptic Membrane Assembly
Receptor Localization To Synapse
Cation Transmembrane Transport
Presynaptic Membrane Assembly
Membrane Hyperpolarization
Regulation Of Synapse Organization
Presynaptic Membrane Organization
Tagcloud
?
17q12
apical
basolateral
defining
disc
discs
dlg2
encodes
germline
guanylate
homology
identity
imaginal
lethal
mediating
member
neoplastic
oncogene
organization
originally
overgrowth
p55
phosphoprotein
polarity
q21
recessive
segment
similarity
Tagcloud (Difference)
?
17q12
apical
basolateral
defining
disc
discs
dlg2
encodes
germline
guanylate
homology
identity
imaginal
lethal
mediating
member
neoplastic
oncogene
organization
originally
overgrowth
p55
phosphoprotein
polarity
q21
recessive
segment
similarity
Tagcloud (Intersection)
?