LPHN1 and ANKS1A

Number of citations of the paper that reports this interaction (PMID 10958799)
9

Data Source:
HPRD (two hybrid)

		LPHN1	ANKS1A
Gene Name		latrophilin 1	ankyrin repeat and sterile alpha motif domain containing 1A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cell Junction Axon Growth Cone Presynaptic Membrane Neuron Projection Synapse	Nucleoplasm Cytoplasm Neuron Projection
	Molecular Function	G-protein Coupled Receptor Activity Protein Binding Latrotoxin Receptor Activity Carbohydrate Binding Cell Adhesion Molecule Binding	Protein Binding
	Biological Process	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules G-protein Coupled Receptor Signaling Pathway Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Synapse Maturation	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Mortality among heart failure patients ( 20400778)	Coronary heart disease ( 21378990) Height ( 23563607 18391951) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661)
Protein-Protein Interactions		9 interactors: ANKS1A APC CACNA1A DLG3 DLG4 PSMA3 ROS1 SHANK1 SHANK2	6 interactors: EGFR ERBB2 ERBB4 LPHN1 UBC YWHAG
Entrez ID		22859	23294
HPRD ID		14305	10610
Ensembl ID			ENSG00000064999
Uniprot IDs		O94910	Q05CP0 Q92625
PDB IDs			2LMR
Enriched GO Terms of Interacting Partners?		Vocalization Behavior Protein Localization To Synapse Synapse Organization Neuron Development Social Behavior Cell Development Receptor Clustering Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Nervous System Development Neuromuscular Process Controlling Balance Synapse Assembly Cell Morphogenesis Involved In Differentiation Receptor Localization To Synapse Dendrite Morphogenesis Neuron Projection Development Generation Of Neurons Cell Projection Morphogenesis Dendritic Spine Morphogenesis Cell Part Morphogenesis Neurogenesis Membrane Depolarization Neuromuscular Process Single-organism Behavior Learning Dendritic Spine Development Dendrite Development Regulation Of Signaling Cell Morphogenesis Dendritic Spine Organization Anatomical Structure Development Adult Behavior Reflex Cell Projection Organization Cell Differentiation Exploration Behavior Synaptic Transmission Behavior Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Ion Transport Developmental Process Positive Regulation Of Excitatory Postsynaptic Membrane Potential Signaling Cell Communication Positive Regulation Of Membrane Potential Learning Or Memory Regulation Of Membrane Potential System Development Cognition	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Fc Receptor Signaling Pathway Regulation Of Kinase Activity Intracellular Signal Transduction Signal Transduction By Phosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Protein Phosphorylation Positive Regulation Of MAPK Cascade Immune Response-regulating Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Kinase Activity Regulation Of Phosphorylation Phosphatidylinositol-mediated Signaling Positive Regulation Of Transferase Activity Cellular Response To Growth Factor Stimulus Regulation Of Phosphorus Metabolic Process Response To Growth Factor Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity Cellular Response To Organic Substance Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Positive Regulation Of Intracellular Transport Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Regulation Of Immune Response Cell Cycle Phase Transition Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Protein Metabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of ERBB Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process
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