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DLG3 and DLGAP3
Number of citations of the paper that reports this interaction (PMID
9115257
)
52
Data Source:
HPRD
(two hybrid)
DLG3
DLGAP3
Gene Name
discs, large homolog 3 (Drosophila)
discs, large (Drosophila) homolog-associated protein 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Plasma Membrane
Tight Junction
Ionotropic Glutamate Receptor Complex
Postsynaptic Density
Basolateral Plasma Membrane
Growth Cone
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex
Neuronal Cell Body
Dendritic Shaft
Postsynaptic Membrane
Postsynaptic Density
Cell Junction
Postsynaptic Membrane
Molecular Function
Guanylate Kinase Activity
Protein Binding
Protein C-terminus Binding
Phosphatase Binding
Protein Phosphatase Binding
PDZ Domain Binding
Ubiquitin Protein Ligase Binding
Ionotropic Glutamate Receptor Binding
Beta-amyloid Binding
Protein Binding
Biological Process
Establishment Of Planar Polarity
Synaptic Transmission
Nervous System Development
Axon Guidance
Negative Regulation Of Cell Proliferation
Negative Regulation Of Phosphatase Activity
Receptor Clustering
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Nucleotide Phosphorylation
Receptor Localization To Synapse
Cell-cell Signaling
Pathways
Axon guidance
L1CAM interactions
NrCAM interactions
Activation of Kainate Receptors upon glutamate binding
Activation of Ca-permeable Kainate Receptor
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Ionotropic activity of Kainate Receptors
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions
40 interactors:
ABCA1
APC
ATP2B4
CACNG2
CALM1
CNKSR2
CRIPT
DLG1
DLG4
DLGAP1
DLGAP3
DLGAP4
ERBB4
EXOC4
EXOC7
GDA
GLS2
GRIK2
GRIN1
GRIN2A
GRIN2B
GRIN2C
GUCY1A2
KCNA4
KCNJ12
KCNJ2
KHDRBS1
KIF1B
LIN7A
LPHN1
LRP2
MAPK12
NLGN1
NLGN2
NLGN3
PTK2B
SCN4A
SCN5A
SEMA4C
SYNGAP1
8 interactors:
DLG1
DLG3
DLG4
DLGAP1
PTK2
PTK2B
SHANK2
SHANK3
Entrez ID
1741
58512
HPRD ID
02177
18935
Ensembl ID
ENSG00000082458
ENSG00000116544
Uniprot IDs
Q59FY1
Q92796
O95886
PDB IDs
1UM7
2FE5
2I1N
Enriched GO Terms of Interacting Partners
?
Membrane Depolarization
Cell-cell Signaling
Synaptic Transmission
Regulation Of Membrane Potential
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Regulation Of Ion Transmembrane Transport
Signaling
Cell Communication
Regulation Of Ion Transport
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Membrane Potential
Regulation Of Synaptic Transmission
Glutamate Receptor Signaling Pathway
Neuron-neuron Synaptic Transmission
Transport
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Membrane Organization
Synaptic Transmission, Glutamatergic
Regulation Of Synaptic Plasticity
Regulation Of Synapse Structure Or Activity
Ion Transmembrane Transport
Regulation Of Signaling
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Receptor Clustering
Protein Localization To Synapse
Neurological System Process
Positive Regulation Of Synaptic Transmission
Regulation Of Receptor Activity
Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Positive Regulation Of Synaptic Transmission, Glutamatergic
Nervous System Development
Regulation Of Synaptic Transmission, Glutamatergic
Transmembrane Transport
Ion Transport
Neuromuscular Process
Regulation Of Respiratory Gaseous Exchange
Regulation Of Signal Transduction
Postsynaptic Membrane Organization
Learning
Regulation Of Long-term Neuronal Synaptic Plasticity
Postsynaptic Membrane Assembly
Receptor Localization To Synapse
Cation Transmembrane Transport
Presynaptic Membrane Assembly
Membrane Hyperpolarization
Regulation Of Synapse Organization
Presynaptic Membrane Organization
Receptor Localization To Synapse
Receptor Clustering
Synaptic Transmission
Vocalization Behavior
Protein Localization To Synapse
Positive Regulation Of Synaptic Transmission
Neuron Projection Development
Establishment Or Maintenance Of Apical/basal Cell Polarity
Cell-cell Signaling
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Neuron Development
Regulation Of Synaptic Plasticity
Positive Regulation Of Membrane Potential
Social Behavior
Establishment Or Maintenance Of Cell Polarity
Neuron Differentiation
Cell Projection Organization
Cell Morphogenesis Involved In Neuron Differentiation
Nervous System Development
Neuron Projection Morphogenesis
Nucleotide Phosphorylation
Regulation Of Membrane Potential
Regulation Of Excitatory Postsynaptic Membrane Potential
Cell Morphogenesis Involved In Differentiation
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Regulation Of Postsynaptic Membrane Potential
Regulation Of Synaptic Transmission
Synapse Assembly
Generation Of Neurons
Signal Complex Assembly
Cell Projection Morphogenesis
Neurogenesis
Cell Part Morphogenesis
Protein Localization To Membrane
Axon Guidance
Cell Development
Response To External Stimulus
Dendritic Spine Morphogenesis
Phosphorylation
Membrane Depolarization
Regulation Of Receptor Activity
Regulation Of Ion Transmembrane Transport
Cellular Component Assembly
Cell Morphogenesis
Learning
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Cytoskeleton Organization
Regulation Of Cytoskeleton Organization
Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity
Tagcloud
?
17q12
apical
basolateral
defining
disc
discs
dlg2
encodes
germline
guanylate
homology
identity
imaginal
lethal
mediating
member
neoplastic
oncogene
organization
originally
overgrowth
p55
phosphoprotein
polarity
q21
recessive
segment
similarity
Tagcloud (Difference)
?
17q12
apical
basolateral
defining
disc
discs
dlg2
encodes
germline
guanylate
homology
identity
imaginal
lethal
mediating
member
neoplastic
oncogene
organization
originally
overgrowth
p55
phosphoprotein
polarity
q21
recessive
segment
similarity
Tagcloud (Intersection)
?