ACTN1 and GRM5

  • Number of citations: 0 (PubMedID 17311919)
  • Data Source: BioGRID (fluorescent resonance energy transfer)

ACTN1

GRM5

Name actinin alpha 1 glutamate metabotropic receptor 5
Structure PDB 2EYI PDB 3LMK
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
GWAS
  • Attention deficit hyperactivity disorder ( 22012869 )
  • Blond vs. brown/black hair color ( 30531825 )
  • Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444 )
  • Depression ( 33859377 )
  • Fish- and plant-related diet ( 32066663 )
  • General factor of neuroticism ( 30867560 )
  • Hair color ( 30664655 )
  • Hypertension ( 31879980 )
  • Neurociticism ( 29500382 )
  • Nonsyndromic cleft lip ( 31609978 )
  • Oily fish consumption ( 32066663 )
  • Pork consumption ( 32066663 )
  • Retinal detachment ( 31816047 )
  • Retinal detachment or retinal break ( 31816047 )
  • Rheumatoid arthritis (ACPA-negative) ( 24532677 )
  • Skin pigmentation ( 30664655 31315583 )
  • Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583 )
  • Skin, hair and eye pigmentation (multivariate analysis) ( 30664655 )
  • Tanning ( 19340012 )
Interacting Genes 93 interacting genes: ACTN3 ADORA2A APC APPBP2 ATXN2 ATXN7 CACNA1A CAMK2A CBY2 CDK5 CDK5R1 CDK5R2 CEBPA CLIC5 COIL COL17A1 CSRP1 CSRP3 CTNNA1 DDIAS DSCAM DYNLT1 EIF2S1 EPM2AIP1 ERBIN FBP1 FILNC1 FXN FXR1 GADD45G GFI1B GIPC1 GIT2 GRIA4 GRIN2A GRM5 GTF2H1 HSPB1 ICAM5 ITGB1 KAT2B KCTD6 KPNA2 LINC01554 LNX1 LPP MAGEA11 MAP2 MAP3K1 MED14 MICALL2 MTDH MTNR1A MTNR1B MYOT MYOZ1 MYOZ2 MYOZ3 NEBL NKAPD1 NR1H3 NUMBL OAS1 PALLD PDHX PDLIM1 PDLIM5 PIAS4 PKD1 PKN1 PLD2 PSEN1 PSMA1 PTK2 PTPN1 PTPN6 PYGB RAVER1 RPS27 SIRPA SLC2A4 SORBS2 SRC SSX2IP SYNPO2L TES TSC1 TTN TXN USP2 VCL XRCC4 ZYX 20 interacting genes: ACTN1 CALM1 CALM2 CALM3 CAMK2A EFNB2 FLNA GPRASP1 HOMER1 HOMER3 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCQ PRKCZ RGS12 SIAH1 TAMALIN
Entrez ID 87 2915
HPRD ID 00020 04980
Ensembl ID ENSG00000072110 ENSG00000168959
Uniprot IDs A0A024R694 A0A7I2V4Y4 A0A804HL31 A0A804HLF4 H9KV75 P12814 A8K5P7 P41594
PDB IDs 2EYI 2EYN 2N8Y 2N8Z 3LMK 4OO9 5CGC 5CGD 6N4X 6N4Y 6N50 6N51 6N52 7FD8 7FD9 8T6J 8T7H 8T8M 8TAO 8X0B 8X0C 8X0D 8X0E 8X0F 8X0G 8X0H
GO Terms Enriched among Interactors