LAMTOR5 and MAF1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAMTOR5	MAF1
Gene Name		late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	MAF1 homolog (S. cerevisiae)
Image
Gene Ontology Annotations	Cellular Component	Lysosome Cytosol Ragulator Complex	Intracellular Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytosol Plasma Membrane Axon Dendrite Intracellular Membrane-bounded Organelle Inhibitory Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold	RNA Polymerase III Core Binding RNA Polymerase III Type 1 Promoter DNA Binding RNA Polymerase III Type 2 Promoter DNA Binding RNA Polymerase III Type 3 Promoter DNA Binding
	Biological Process	Regulation Of Cell Size Response To Virus Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase III Promoter Transcription Factor TFIIIB Complex Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CEP70 EEF1A1 GAPDH GIT1 GPRASP1 KIAA1377 LAMTOR4 LRIF1 MAF1 MEOX2 NCOA6 RABIF TAF9 UTP14A YTHDC1 ZBTB16	8 interactors: ARMCX3 CCND3 CSNK2A1 CSNK2A2 LAMTOR5 MTOR NUDT3 SUMO2
Entrez ID		10542	84232
HPRD ID		09773	14345
Ensembl ID		ENSG00000134248	ENSG00000179632
Uniprot IDs		O43504	Q9H063
PDB IDs		3MS6 3MSH	3NR5
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Factor TFIIIB Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Gene Expression Neuron Death Nucleobase-containing Compound Metabolic Process G-protein Coupled Receptor Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Embryonic Pattern Specification Protein Stabilization Negative Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Stability Male Germ-line Stem Cell Asymmetric Division Somite Specification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Glucocorticoid Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Macromolecule Biosynthetic Process	Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteolysis Positive Regulation Of Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Processing Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Protein Processing Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Diphosphoinositol Polyphosphate Catabolic Process Regulation Of Carbohydrate Utilization Diadenosine Polyphosphate Catabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Chromosome Organization Positive Regulation Of Protein Metabolic Process Protein Phosphorylation Response To Amino Acid Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Cell Size Negative Regulation Of Mitotic Cell Cycle Phase Transition Phosphate-containing Compound Metabolic Process Mitotic Cell Cycle Checkpoint Cellular Protein Modification Process Regulation Of Metabolic Process Response To External Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Phosphorylation Regulation Of Chromosome Organization Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of NFAT Protein Import Into Nucleus Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Phase Transition
Tagcloud ?			5s affects alcohol brca1 decreases deregulation emerging enhances iii importantly leu mcf pol prb promote pten repress represses repression restoring rrna slightly suppressors tightly transformation translational trna truncated uncover
Tagcloud (Difference) ?			5s affects alcohol brca1 decreases deregulation emerging enhances iii importantly leu mcf pol prb promote pten repress represses repression restoring rrna slightly suppressors tightly transformation translational trna truncated uncover
Tagcloud (Intersection) ?