LAMTOR5 and YTHDC1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LAMTOR5	YTHDC1
Gene Name		late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	YTH domain containing 1
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Gene Ontology Annotations	Cellular Component	Lysosome Cytosol Ragulator Complex	Nucleus Nuclear Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold	RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Cell Size Response To Virus Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus	MRNA Splice Site Selection
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		16 interactors: CEP70 EEF1A1 GAPDH GIT1 GPRASP1 KIAA1377 LAMTOR4 LRIF1 MAF1 MEOX2 NCOA6 RABIF TAF9 UTP14A YTHDC1 ZBTB16	34 interactors: ABL1 ADAMTS4 CFH CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPT10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51
Entrez ID		10542	91746
HPRD ID		09773	11689
Ensembl ID		ENSG00000134248	ENSG00000083896
Uniprot IDs		O43504	J3QR07 Q96MU7
PDB IDs		3MS6 3MSH	2YUD
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Factor TFIIIB Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Gene Expression Neuron Death Nucleobase-containing Compound Metabolic Process G-protein Coupled Receptor Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Embryonic Pattern Specification Protein Stabilization Negative Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Stability Male Germ-line Stem Cell Asymmetric Division Somite Specification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Glucocorticoid Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Macromolecule Biosynthetic Process	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Protein Autophosphorylation Regulation Of Cell-cell Adhesion RNA Metabolic Process Peptidyl-tyrosine Phosphorylation Regulation Of Wnt Signaling Pathway Gene Expression Viral Process Innate Immune Response Regulation Of Cell Proliferation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Regulation Of Cell Adhesion Anatomical Structure Development Leukocyte Migration Regulation Of Canonical Wnt Signaling Pathway Immune Response Regulation Of RNA Metabolic Process Regulation Of Intracellular Transport Cytoplasmic Transport Defense Response Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Activated T Cell Proliferation Phagocytosis Positive Regulation Of Viral Genome Replication Regulation Of Neuron Death Heterocycle Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Aromatic Compound Metabolic Process Nuclear Export Regulation Of T Cell Activation Nucleus Organization Regulation Of Gene Expression Developmental Process Regulation Of Nitrogen Compound Metabolic Process Antigen Receptor-mediated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Cellular Process Golgi To Plasma Membrane Transport
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