THRAP3

Description		thyroid hormone receptor associated protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mediator Complex Nuclear Speck Exon-exon Junction Complex Extracellular Exosome
	Molecular Function	Nucleotide Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity RNA Binding Protein Binding ATP Binding Nuclear Vitamin D Receptor Binding Nuclear Thyroid Hormone Receptor Binding Phosphoprotein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process MRNA Processing Circadian Rhythm RNA Splicing Positive Regulation Of Circadian Rhythm Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Rhythmic Process
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		13 interacting genes: APBB1 CEBPA CLK1 CSNK2A1 NEDD4 OGT PIN1 RNF10 SHANK3 SREK1 USP7 WEE2-AS1 YWHAG
Entrez ID		9967
HPRD ID		07543
Ensembl ID		ENSG00000054118
Uniprot IDs		Q9Y2W1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Catabolic Process Protein Localization To Vacuole Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Phosphothreonine Residue Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Phosphoserine Residue Binding Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Intracellular Signal Transduction Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Targeting Negative Regulation Of Proteasomal Protein Catabolic Process Protein Localization To Lysosome TORC1 Signaling Protein Stabilization Negative Regulation Of Proteolysis Involved In Protein Catabolic Process TOR Signaling Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of TORC1 Signaling Cellular Response To Stress Regulation Of Translational Initiation Proline-rich Region Binding Signal Transduction Sin3-type Complex Negative Regulation Of Macromolecule Metabolic Process Regulation Of Proteolysis Negative Regulation Of Proteolysis Regulation Of Protein Stability Negative Regulation Of Catabolic Process Positive Regulation Of Metabolic Process Regulation Of TOR Signaling Postsynaptic Cytosol Ionotropic Glutamate Receptor Binding Negative Regulation Of Metabolic Process Regulation Of Gene Expression Negative Regulation Of Signal Transduction Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Localization Response To Nutrient Levels Regulation Of Primary Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Protein Catabolic Process
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