Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
EFTUD2 and LSM8
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
EFTUD2
LSM8
Gene Name
elongation factor Tu GTP binding domain containing 2
LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Cajal Body
Membrane
Nuclear Speck
Catalytic Step 2 Spliceosome
Spliceosomal Complex
U4/U6 X U5 Tri-snRNP Complex
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Poly(A) RNA Binding
Protein Binding
U6 SnRNA Binding
U6 SnRNA 3'-end Binding
Poly(A) RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
MRNA Splicing, Via Spliceosome
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
16 interactors:
ARPC3
CYFIP1
GOLM1
GSK3B
HINFP
HSPB1
LSM8
PIN1
PRPF6
PRPF8
SF1
SF3B3
SF3B4
SNRNP40
SREK1
WBP4
49 interactors:
ARNT
BCKDK
COL23A1
DBF4
DCP1A
DCP1B
DPAGT1
ECHDC2
EFTUD2
EXOSC10
EXOSC6
FAM63A
FERMT3
GMPPA
GTF2I
HSPA9
IFNLR1
IGHMBP2
ISOC2
ITSN2
KCTD3
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MGA
MPRIP
MRPL48
MTHFR
NAGK
NME4
PDCD2
PGD
PHF11
RBM5
RPL24
RSC1A1
RSL24D1
SEPT10
SEPT5
SMU1
SNRNP200
SNRPB
SNRPD1
TALDO1
THUMPD3
UPF1
Entrez ID
9343
51691
HPRD ID
04869
06288
Ensembl ID
ENSG00000108883
Uniprot IDs
B3KX19
B4DMC0
K7EJ81
Q15029
A4D0W0
O95777
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Processing
MRNA Metabolic Process
RNA Processing
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Spliceosomal Tri-snRNP Complex Assembly
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Spliceosomal SnRNP Assembly
Positive Regulation Of Cellular Metabolic Process
Spliceosomal Complex Assembly
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Type B Pancreatic Cell Development
Superior Temporal Gyrus Development
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Negative Regulation Of Phosphorylation
Positive Regulation Of Organelle Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Gene Expression
Regulation Of Organelle Organization
Hypermethylation Of CpG Island
Primary Sex Determination
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Positive Regulation Of Cellular Biosynthetic Process
MRNA 3'-splice Site Recognition
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Cellular Response To Interleukin-3
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Female Gonad Development
Positive Regulation Of Metabolic Process
Negative Regulation Of Glycogen (starch) Synthase Activity
Regulation Of Neuron Maturation
Axonogenesis
Negative Regulation Of MAPK Cascade
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Protein Localization To Microtubule
Positive Regulation Of Actin Nucleation
Negative Regulation Of Dendrite Morphogenesis
Positive Regulation Of Endothelial Cell Chemotaxis
Positive Regulation Of Protein Complex Assembly
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Nuclear-transcribed MRNA Catabolic Process
MRNA Metabolic Process
MRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
RNA Catabolic Process
Nucleobase-containing Compound Metabolic Process
Aromatic Compound Catabolic Process
RNA Splicing
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
MRNA Processing
RNA Processing
Catabolic Process
Gene Expression
RNA Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Cellular Macromolecule Catabolic Process
Ribonucleoprotein Complex Biogenesis
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cellular Metabolic Process
Histone MRNA Metabolic Process
Pentose Biosynthetic Process
Metabolic Process
Histone MRNA Catabolic Process
Dosage Compensation By Inactivation Of X Chromosome
Spliceosomal Complex Assembly
Dosage Compensation
Ribonucleoprotein Complex Assembly
Ribosome Biogenesis
Pentose-phosphate Shunt
Glyceraldehyde-3-phosphate Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Glucose 6-phosphate Metabolic Process
RRNA Processing
NcRNA Metabolic Process
Starch Catabolic Process
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Response To Type III Interferon
Dolichol Biosynthetic Process
NADP Metabolic Process
RRNA Metabolic Process
Spliceosomal SnRNP Assembly
Carbohydrate Biosynthetic Process
D-gluconate Metabolic Process
Response To Vitamin B2
Tagcloud
?
3k36me3
antagonizing
arranged
bromo
bs69
called
chromatin
connects
decorated
depends
h3k36me3
identifies
intron
ir
modalities
phd
pwwp
reader
recognizes
remarkably
retention
reveals
snrnp
spliceosome
splicing
tandemly
trimethylation
u5
zmynd11
Tagcloud (Difference)
?
3k36me3
antagonizing
arranged
bromo
bs69
called
chromatin
connects
decorated
depends
h3k36me3
identifies
intron
ir
modalities
phd
pwwp
reader
recognizes
remarkably
retention
reveals
snrnp
spliceosome
splicing
tandemly
trimethylation
u5
zmynd11
Tagcloud (Intersection)
?