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EFTUD2 and ARPC3
Number of citations of the paper that reports this interaction (PubMedID
28515276
)
62
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
HPRD
(two hybrid)
EFTUD2
ARPC3
Description
elongation factor Tu GTP binding domain containing 2
actin related protein 2/3 complex subunit 3
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytosol
Cajal Body
Membrane
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U2-type Precatalytic Spliceosome
U2-type Catalytic Step 2 Spliceosome
Catalytic Step 2 Spliceosome
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Arp2/3 Protein Complex
Focal Adhesion
Actin Cytoskeleton
Membrane
Lamellipodium
Cell Leading Edge
Filamentous Actin
Site Of Double-strand Break
Cell Projection
Growth Cone Leading Edge
Extracellular Exosome
Molecular Function
Nucleotide Binding
RNA Binding
GTPase Activity
Protein Binding
GTP Binding
U5 SnRNA Binding
Actin Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Actin Filament Binding
Biological Process
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Response To Cocaine
Cellular Response To Xenobiotic Stimulus
Regulation Of Actin Filament Polymerization
Arp2/3 Complex-mediated Actin Nucleation
Actin Polymerization-dependent Cell Motility
Regulation Of Synaptic Vesicle Endocytosis
Cellular Response To Nerve Growth Factor Stimulus
Pathways
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Asthma (
31619474
)
Craniofacial microsomia (
26853712
)
Automobile speeding propensity (
30643258
)
Bipolar disorder (
31043756
)
Femoral neck bone mineral density (
30172743
)
Interacting Genes
15 interacting genes:
ARPC3
CYFIP1
DUX4
GOLM1
GSK3B
HINFP
LSM8
PIN1
PRPF6
SF3B3
SF3B4
SREK1
SUMO2
USP7
WBP4
31 interacting genes:
ACTR3
ARAP1
ARPC4
BAG6
CCR10
CDKN2B
CEBPA
CETP
DUSP29
EFTUD2
FAM9A
GOLGA2
HOXA3
LATS1
LGALS4
LTA4H
MAPK6
NRIP1
OTUD5
POU2F1
PRMT1
RBBP8NL
RETREG3
RPS4X
SYBU
TARS3
THNSL2
WAS
WASF2
WASL
ZNF576
Entrez ID
9343
10094
HPRD ID
04869
09175
Ensembl ID
ENSG00000108883
ENSG00000111229
Uniprot IDs
B3KX19
Q15029
O15145
PDB IDs
3JCR
5MQF
5O9Z
5XJC
5YZG
5Z56
5Z57
5Z58
6AH0
6AHD
6FF4
6FF7
6ICZ
6ID0
6ID1
6QDV
6QW6
6QX9
6ZYM
7AAV
7ABF
7ABG
7ABI
7DVQ
7QTT
7W59
7W5A
7W5B
8C6J
8CH6
8H6E
8H6J
8H6K
8H6L
8I0P
8I0R
8I0S
8I0T
8I0U
8I0V
8I0W
8Q7N
8Q7Q
8Q7V
8Q7W
8Q7X
8Q91
8QO9
8QOZ
8QP8
8QP9
8QPA
8QPB
8QPE
8QPK
8QXD
8QZS
8R08
8R09
8R0A
8R0B
8RC0
8RM5
8RO2
8Y6O
9FMD
6UHC
6YW6
6YW7
8P94
Enriched GO Terms of Interacting Partners
?
U2-type Precatalytic Spliceosome
Spliceosomal Complex
MRNA Splicing, Via Spliceosome
Precatalytic Spliceosome
RNA Splicing
RNA Splicing, Via Transesterification Reactions
MRNA Processing
Negative Regulation Of Protein Catabolic Process
Spliceosomal Complex Assembly
MRNA Metabolic Process
Nucleoplasm
Regulation Of Protein Catabolic Process
RNA Processing
RNA Metabolic Process
Negative Regulation Of Protein Metabolic Process
Nucleic Acid Metabolic Process
U2-type Prespliceosome Assembly
U12-type Spliceosomal Complex
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
U2 SnRNP
Postsynaptic Cytosol
U2-type Spliceosomal Complex
Negative Regulation Of Catabolic Process
Positive Regulation Of RNA Biosynthetic Process
Nucleus
Positive Regulation Of DNA-templated Transcription
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Nuclear Speck
Cellular Component Assembly
Positive Regulation Of Transcription By RNA Polymerase II
U4/U6 X U5 Tri-snRNP Complex
Positive Regulation Of RNA Metabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Tau Protein Binding
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Macromolecule Metabolic Process
Regulation Of Microtubule Anchoring At Centrosome
Cis-trans Isomerase Activity
Growth Cone Leading Edge
Protein-RNA Complex Assembly
Nucleobase-containing Compound Metabolic Process
Postsynapse
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Leading Edge
Glutamatergic Synapse
Negative Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Nucleic Acid Binding
Superior Temporal Gyrus Development
Negative Regulation Of Type B Pancreatic Cell Development
Regulation Of Cell Projection Assembly
Negative Regulation Of Actin Filament Bundle Assembly
Actin Filament Polymerization
Regulation Of Lamellipodium Assembly
Negative Regulation Of Stress Fiber Assembly
Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly
Regulation Of Actin Filament Organization
Actin Filament Organization
Regulation Of Lamellipodium Organization
Arp2/3 Protein Complex
Actin Polymerization Or Depolymerization
Actin Cytoskeleton
Actin Filament-based Movement
HMG Box Domain Binding
Asymmetric Cell Division
Protein Polymerization
Regulation Of Actin Cytoskeleton Organization
Nucleus
Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Cell Projection Organization
Actin Binding
Regulation Of Actin Filament-based Process
Regulation Of Stress Fiber Assembly
Regulation Of Supramolecular Fiber Organization
Site Of Double-strand Break
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