SAT1 and KCNA4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAT1	KCNA4
Gene Name		spermidine/spermine N1-acetyltransferase 1	potassium channel, voltage gated shaker related subfamily A, member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Axon
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding Spermidine Binding	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Ion Binding
	Biological Process	Angiogenesis Polyamine Metabolic Process Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Small Molecule Metabolic Process	Potassium Ion Transport Synaptic Transmission Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport
Pathways		Metabolism of polyamines Interconversion of polyamines Metabolism of amino acids and derivatives	Potassium Channels Voltage gated Potassium channels
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS
Protein-Protein Interactions		75 interactors: ABCB8 APLP1 B4GALT3 C14orf1 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DMRT3 DNPEP EEF1G EIF3D EPHB6 EVA1A FAM156A FAM69B FAM86C1 FTSJ3 FUNDC2 GBP2 GDF9 GNB2L1 HIF1A HOXB6 HOXB9 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KIAA1377 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1	16 interactors: ACTN2 CASK DLG1 DLG2 DLG3 DLG4 DLGAP1 ERBB2IP INADL KCNA2 LNX1 NDUFA4L2 NEU1 SAT1 SNTA1 SNTG1
Entrez ID		6303	3739
HPRD ID		02431	01444
Ensembl ID		ENSG00000130066	ENSG00000182255
Uniprot IDs		P21673 Q6ICU9	P22459
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of RNA Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Response To External Stimulus Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Response To Light Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Locomotion Regulation Of Interleukin-12 Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Axon Guidance Response To Abiotic Stimulus	Receptor Localization To Synapse Nucleotide Phosphorylation Protein Localization To Synapse Synaptic Transmission Establishment Or Maintenance Of Apical/basal Cell Polarity Cell-cell Signaling Receptor Clustering Regulation Of Ion Transmembrane Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Membrane Potential Nucleotide Metabolic Process Regulation Of Ion Transport Nucleobase-containing Small Molecule Metabolic Process Establishment Or Maintenance Of Cell Polarity Organophosphate Metabolic Process Protein Localization To Membrane Cell Communication Cortical Actin Cytoskeleton Organization Positive Regulation Of Potassium Ion Transport Cortical Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Ion Transport Cell Junction Assembly Small Molecule Metabolic Process Cell-cell Junction Organization Muscle Contraction Tight Junction Assembly Signaling Protein Homooligomerization Muscle System Process Cellular Component Assembly Negative Regulation Of Phosphatase Activity Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Negative Regulation Of Dephosphorylation Apical Junction Assembly Cellular Protein Localization Positive Regulation Of Ion Transmembrane Transport Optic Nerve Structural Organization Spermidine Acetylation Basal Protein Localization Action Potential Sensory Perception Of Pain Membrane Organization Axon Guidance Regulation Of Phosphatase Activity Putrescine Catabolic Process Protein Oligomerization Cellular Localization
Tagcloud ?		acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Difference) ?		acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Intersection) ?