SAT1 and DDX39A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SAT1	DDX39A
Description		spermidine/spermine N1-acetyltransferase 1	DExD-box helicase 39A
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Identical Protein Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation	MRNA Splicing, Via Spliceosome Toll-like Receptor Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing Negative Regulation Of Innate Immune Response Negative Regulation Of RNA Export From Nucleus
Pathways		Interconversion of polyamines	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	14 interacting genes: CCL14 CEBPA DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 RNF4 SARNP SAT1 SUMO2 TERF1 TERF2IP UBE2I
Entrez ID		6303	10212
HPRD ID		02431	10861
Ensembl ID		ENSG00000130066	ENSG00000123136
Uniprot IDs		A0A384NQ10 P21673	O00148
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	8IJU
Enriched GO Terms of Interacting Partners?		Protein Binding Chromatin	PML Body Regulation Of Ubiquitin-dependent Protein Catabolic Process Nuclear Body Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping G-rich Strand Telomeric DNA Binding Transcription Export Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process SUMO Transferase Activity RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomerase Nuclear Export Regulation Of Proteolysis Nucleus Nuclear Chromosome Presynaptic Cytosol Postsynaptic Cytosol Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Positive Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Proteolysis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Protein Metabolic Process RNA Binding Spermidine Binding Protein Sumoylation Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly SUMO Conjugating Enzyme Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Regulation Of Metabolic Process Nuclear Transport Nucleocytoplasmic Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process
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