SAT1 and EIF3D

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SAT1	EIF3D
Description		spermidine/spermine N1-acetyltransferase 1	eukaryotic translation initiation factor 3 subunit D
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Cap-dependent Translational Initiation Translation Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways		Interconversion of polyamines	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	33 interacting genes: ANKRD28 BEND5 CCDC125 CCDC57 CDC42 CEP70 CREBBP DNAJB11 DVL3 EIF3G EIF3J EIF3L EIF5 ERCC6 GOLGA6L9 HOMER3 HOOK2 HSF2BP KIFC3 LZTS2 MORN3 MTUS2 OGT PHLDA1 PICK1 POLR2G REL RNF10 RSPH1 SAT1 TFIP11 TRIM23 TRIM27
Entrez ID		6303	8664
HPRD ID		02431	04888
Ensembl ID		ENSG00000130066	ENSG00000100353
Uniprot IDs		A0A384NQ10 P21673	O15371
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	6YBD 6YBS 6ZMW 6ZON 6ZP4 6ZVJ 7A09 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8RG0 8XXN 9BLN
Enriched GO Terms of Interacting Partners?		Protein Binding Chromatin	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasm Translation Initiation Factor Activity Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Translational Initiation Viral Translational Termination-reinitiation Cytoplasmic Translational Initiation Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Centrosome Identical Protein Binding Protein Binding Cytosol Translation Protein-RNA Complex Assembly
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