SAT1 and MRPL9

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		SAT1	MRPL9
Description		spermidine/spermine N1-acetyltransferase 1	mitochondrial ribosomal protein L9
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation	Translation Mitochondrial Translation
Pathways		Interconversion of polyamines	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Asthma ( 31619474)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	5 interacting genes: CA12 CDC37 FAM9B HNRNPK SAT1
Entrez ID		6303	65005
HPRD ID		02431	14774
Ensembl ID		ENSG00000130066	ENSG00000143436
Uniprot IDs		A0A384NQ10 P21673	Q5SZR1 Q9BYD2
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Protein Binding Chromatin	Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding HSP90-CDC37 Chaperone Complex Positive Regulation Of Low-density Lipoprotein Particle Clearance Diamine N-acetyltransferase Activity Polyamine Catabolic Process Monoatomic Anion Homeostasis Chloride Ion Homeostasis Estrous Cycle Carbonate Dehydratase Activity Ovulation Cycle Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of MRNA Splicing, Via Spliceosome Regulatory NcRNA-mediated Heterochromatin Formation Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Random Inactivation Of X Chromosome Spermidine Metabolic Process Polyamine Biosynthetic Process N-acetyltransferase Activity Polyamine Metabolic Process Putrescine Metabolic Process Protein Kinase Regulator Activity Positive Regulation Of Mitophagy Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Positive Regulation Of Type 2 Mitophagy Synaptonemal Complex Negative Regulation Of RNA Splicing Positive Regulation Of Autophagy Of Mitochondrion
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