SAT1 and COX6C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAT1	COX6C
Description		spermidine/spermine N1-acetyltransferase 1	cytochrome c oxidase subunit 6C
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Membrane Respiratory Chain Complex IV
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding	Protein Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation	Generation Of Precursor Metabolites And Energy Oxidative Phosphorylation Mitochondrial Electron Transport, Cytochrome C To Oxygen Cellular Respiration
Pathways		Interconversion of polyamines	TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1 Complex IV assembly
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine	Cholic Acid N-Formylmethionine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Glucose homeostasis traits ( 25524916) Leukocyte telomere length ( 32109421)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	4 interacting genes: PHB1 PTN RCHY1 SAT1
Entrez ID		6303	1345
HPRD ID		02431	00494
Ensembl ID		ENSG00000130066	ENSG00000164919
Uniprot IDs		A0A384NQ10 P21673	A0A024R9B7 P09669
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	5Z62
Enriched GO Terms of Interacting Partners?		Protein Binding Chromatin	DNA Biosynthetic Process Mitochondrial Prohibitin Complex Complement Component C3a Binding Dendrite Regeneration Spermidine Acetylation Putrescine Catabolic Process Spermidine Binding Proteinase Activated Receptor Binding Ossification Involved In Bone Remodeling Diamine N-acetyltransferase Activity Polyamine Catabolic Process T-helper 17 Type Immune Response Error-free Translesion Synthesis Positive Regulation Of Complement Activation Negative Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Host-mediated Perturbation Of Viral RNA Genome Replication RIG-I Signaling Pathway Positive Regulation Of Axon Regeneration Leukocyte Chemotaxis Involved In Inflammatory Response Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Spermidine Metabolic Process Putrescine Metabolic Process Regulation Of Protein Catabolic Process Progesterone Receptor Signaling Pathway Complement Component C3b Binding Dendrite Arborization Negative Regulation Of Long-term Synaptic Potentiation Chondroitin Sulfate Binding Positive Regulation Of Hepatocyte Proliferation Estrous Cycle Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Neuroblast Proliferation Regulation Of Cell Population Proliferation Regulation Of Hepatocyte Proliferation Positive Regulation Of Dendrite Development Polyamine Biosynthetic Process N-acetyltransferase Activity Cellular Response To Interleukin-6 Negative Regulation Of Androgen Receptor Signaling Pathway Ovulation Cycle Polyamine Metabolic Process Response To Interleukin-6 Neuron Projection Arborization Response To Auditory Stimulus Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Humoral Immune Response Positive Regulation Of Stem Cell Differentiation Regulation Of Complement Activation Decidualization
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