SAT1 and CCDC148

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SAT1	CCDC148
Description		spermidine/spermine N1-acetyltransferase 1	coiled-coil domain containing 148
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Spermidine Binding Identical Protein Binding	Protein Binding
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Population Proliferation
Pathways		Interconversion of polyamines
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases		Keratosis follicularis spinulosa decalvans
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Cerebrospinal fluid AB1-42 levels ( 28247064) Major depressive disorder x sex interaction ( 34099189) Restless legs syndrome ( 29029846 33239738)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 SPMIP10 TACO1 TCF25 TEAD4 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	3 interacting genes: SAT1 SNX1 USHBP1
Entrez ID		6303	130940
HPRD ID		02431	14046
Ensembl ID		ENSG00000130066	ENSG00000153237
Uniprot IDs		A0A384NQ10 P21673	Q8NFR7
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		Protein Binding Chromatin	Diamine N-acetyltransferase Activity Spermidine Acetylation Putrescine Catabolic Process Polyamine Catabolic Process Spermidine Binding Retromer, Tubulation Complex Leptin Receptor Binding Spermidine Metabolic Process Putrescine Metabolic Process Lamellipodium Morphogenesis Transferrin Receptor Binding Polyamine Biosynthetic Process N-acetyltransferase Activity Polyamine Metabolic Process Early Endosome To Golgi Transport Retromer Complex Insulin Receptor Binding Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Epidermal Growth Factor Receptor Binding Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Lamellipodium Organization Biogenic Amine Metabolic Process Receptor Internalization
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