SAT1 and DMRT3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SAT1	DMRT3
Gene Name		spermidine/spermine N1-acetyltransferase 1	doublesex and mab-3 related transcription factor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol	Nucleus
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding Spermidine Binding	Core Promoter Proximal Region Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Angiogenesis Polyamine Metabolic Process Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Proliferation Small Molecule Metabolic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Sex Differentiation Adult Walking Behavior Transmission Of Nerve Impulse Ventral Spinal Cord Interneuron Specification Regulation Of Odontogenesis Of Dentin-containing Tooth Male Sex Differentiation
Pathways		Metabolism of polyamines Interconversion of polyamines Metabolism of amino acids and derivatives
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS			Major depressive disorder ( 23377640)
Protein-Protein Interactions		75 interactors: ABCB8 APLP1 B4GALT3 C14orf1 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DMRT3 DNPEP EEF1G EIF3D EPHB6 EVA1A FAM156A FAM69B FAM86C1 FTSJ3 FUNDC2 GBP2 GDF9 GNB2L1 HIF1A HOXB6 HOXB9 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KIAA1377 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1	26 interactors: CCNDBP1 INCA1 KHDRBS3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 MDFI MGAT5B MID2 MTUS2 NOTCH2NL PLSCR1 PSMA3 RBPMS REL SAT1 TCF4 TRAF1 TRIM23 TRIM27 TRIP6 UBASH3B
Entrez ID		6303	58524
HPRD ID		02431	16827
Ensembl ID		ENSG00000130066	ENSG00000064218
Uniprot IDs		P21673 Q6ICU9	Q9NQL9
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Cellular Process Regulation Of RNA Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Response To External Stimulus Negative Regulation Of Oxidative Stress-induced Neuron Death Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Gene Expression Chemotaxis Response To Light Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Locomotion Regulation Of Interleukin-12 Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Response To Ionizing Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Axon Guidance Response To Abiotic Stimulus	Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Viral Process Regulation Of Intracellular Protein Transport Regulation Of Signaling Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Transferase Activity Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Transport Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Localization Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Establishment Of Protein Localization Regulation Of Protein Metabolic Process Regulation Of Viral Process Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Protein Kinase Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Kinase Activity Positive Regulation Of Intracellular Transport Regulation Of Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Cellular Process Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Phosphorylation Regulation Of Viral Transcription Spermidine Acetylation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway
Tagcloud ?		acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Difference) ?		acetyltransferase biologic catabolism chemoradiation databases dr dramatic explaining gbm glioblastoma ionizing lies mechanistically multiforme n1 neurosphere oncomine polyamine radiation radioresistance radiosensitization recombination referenced rembrandt sensitization sensitize shrna spermidine spermine
Tagcloud (Intersection) ?