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GNA13 and RIC8A
Number of citations of the paper that reports this interaction (PMID
12509430
)
65
Data Source:
HPRD
(in vitro, two hybrid)
GNA13
RIC8A
Gene Name
guanine nucleotide binding protein (G protein), alpha 13
RIC8 guanine nucleotide exchange factor A
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Heterotrimeric G-protein Complex
Plasma Membrane
Focal Adhesion
Membrane
Brush Border Membrane
Melanosome
Extracellular Vesicular Exosome
Cytoplasm
Plasma Membrane
Molecular Function
GTPase Activity
Signal Transducer Activity
Protein Binding
GTP Binding
G-protein Beta/gamma-subunit Complex Binding
Type 1 Angiotensin Receptor Binding
D5 Dopamine Receptor Binding
Metal Ion Binding
G-protein Alpha-subunit Binding
Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Patterning Of Blood Vessels
In Utero Embryonic Development
Movement Of Cell Or Subcellular Component
Signal Transduction
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Rho Protein Signal Transduction
Blood Coagulation
Regulation Of Cell Shape
Cell Differentiation
Platelet Activation
Regulation Of Cell Migration
Activation Of Phospholipase D Activity
In Utero Embryonic Development
Vasculature Development
G-protein Coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Visual Learning
Cell Migration Involved In Gastrulation
Positive Regulation Of GTPase Activity
Cell-cell Adhesion Involved In Gastrulation
Basement Membrane Organization
Pathways
Thrombin signalling through proteinase activated receptors (PARs)
Signaling by GPCR
GPCR downstream signaling
Thromboxane signalling through TP receptor
G alpha (12/13) signalling events
Signal amplification
Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Uterine fibroids (
21460842
)
Protein-Protein Interactions
31 interactors:
AIP
AKAP3
ARHGEF1
ARHGEF11
ARHGEF12
CDH1
CDH2
CTNNB1
CXCR4
DRD5
EDNRB
F2R
GNA12
GPR17
MCF2
MTNR1A
PPP5C
PRKACA
PRKCB
PRKCD
PRKCE
PTK2B
RDX
RGS16
RIC8A
S1PR2
S1PR3
S1PR4
TBXA2R
TGFBR1
TSHR
20 interactors:
EFEMP1
GNA13
GNAI1
GNAI2
GNAI3
GNAO1
GNAQ
GNAS
MAPK8IP3
NECAB2
NUTM1
RABAC1
SDCBP
TERF1
TUBB2A
UBQLN1
UBQLN4
XPO1
ZDHHC17
ZNF585B
Entrez ID
10672
60626
HPRD ID
05100
12373
Ensembl ID
ENSG00000120063
ENSG00000177963
Uniprot IDs
B7Z7R0
F5H1G8
Q14344
Q9NPQ8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Regulation Of Intracellular Signal Transduction
Signal Transduction
Positive Regulation Of Catalytic Activity
Cellular Calcium Ion Homeostasis
Calcium Ion Homeostasis
G-protein Coupled Receptor Signaling Pathway
Signaling
Regulation Of Signaling
Cell Communication
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Cellular Response To Stimulus
Cytosolic Calcium Ion Homeostasis
Cellular Metal Ion Homeostasis
Cellular Cation Homeostasis
Cellular Ion Homeostasis
Metal Ion Homeostasis
Response To Organic Substance
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cell Activation
Cellular Chemical Homeostasis
Ion Homeostasis
Apoptotic Process
Programmed Cell Death
Response To Stimulus
Positive Regulation Of Hydrolase Activity
Cellular Response To Organic Substance
Cell Death
Death
Chemical Homeostasis
Cellular Homeostasis
Regulation Of Cellular Process
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Intracellular Signal Transduction
Regulation Of Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of MAPK Cascade
Regulation Of MAPK Cascade
Platelet Activation
Homeostatic Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Signaling
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of Phosphorus Metabolic Process
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Termination Of Signal Transduction
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Platelet Activation
Blood Coagulation
Hemostasis
Dopamine Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Regulation Of Cyclase Activity
Regulation Of Metabolic Process
Signal Transduction
Regulation Of CAMP Biosynthetic Process
Cellular Response To Stimulus
Regulation Of CAMP Metabolic Process
Signaling
Cell Communication
Response To Stimulus
Regulation Of Catalytic Activity
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Post-embryonic Development
Regulation Of Cellular Process
Negative Regulation Of CAMP Biosynthetic Process
Positive Regulation Of Intracellular Signal Transduction
Cell Division
Response To Stress
Negative Regulation Of CAMP Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Response To Drug
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Catalytic Activity
Vesicle Fusion
Synaptic Transmission
Post-embryonic Body Morphogenesis
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Phospholipase Activity
Organelle Fusion
Positive Regulation Of Signal Transduction
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Regulation Of Cellular Protein Metabolic Process
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Tagcloud
?
18q
19p13
1q
aberrations
arising
burkitt
collaborating
cooperate
copy
deep
enhancer
gains
id3
immunoglobulin
lymphoma
microrna
myc
next
profiling
recurrent
scope
sequencing
signatures
smarca4
subgroups
summary
transcriptome
widened
yielded
Tagcloud (Difference)
?
18q
19p13
1q
aberrations
arising
burkitt
collaborating
cooperate
copy
deep
enhancer
gains
id3
immunoglobulin
lymphoma
microrna
myc
next
profiling
recurrent
scope
sequencing
signatures
smarca4
subgroups
summary
transcriptome
widened
yielded
Tagcloud (Intersection)
?