GNA13 and RDX

Number of citations of the paper that reports this interaction (PMID 10816569)
17

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		GNA13	RDX
Gene Name		guanine nucleotide binding protein (G protein), alpha 13	radixin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Vesicular Exosome	Ruffle Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Extrinsic Component Of Membrane Lamellipodium Filopodium T-tubule Cleavage Furrow Stereocilium Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	GTPase Activity Signal Transducer Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Type 1 Angiotensin Receptor Binding D5 Dopamine Receptor Binding Metal Ion Binding	Actin Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Patterning Of Blood Vessels In Utero Embryonic Development Movement Of Cell Or Subcellular Component Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Blood Coagulation Regulation Of Cell Shape Cell Differentiation Platelet Activation Regulation Of Cell Migration Activation Of Phospholipase D Activity	Positive Regulation Of Gene Expression Microvillus Assembly Apical Protein Localization Actin Filament Capping Establishment Of Endothelial Barrier
Pathways		Thrombin signalling through proteinase activated receptors (PARs) Signaling by GPCR GPCR downstream signaling Thromboxane signalling through TP receptor G alpha (12/13) signalling events Signal amplification Platelet activation, signaling and aggregation	Axon guidance L1CAM interactions Recycling pathway of L1
Drugs
Diseases
GWAS
Protein-Protein Interactions		31 interactors: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR	16 interactors: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1
Entrez ID		10672	5962
HPRD ID		05100	01534
Ensembl ID		ENSG00000120063	ENSG00000137710
Uniprot IDs		B7Z7R0 F5H1G8 Q14344	B0YJ88 P35241 Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Signal Transduction Positive Regulation Of Catalytic Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Signaling Cell Communication Regulation Of Catalytic Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cytosolic Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Activation Cellular Chemical Homeostasis Ion Homeostasis Apoptotic Process Programmed Cell Death Response To Stimulus Positive Regulation Of Hydrolase Activity Cellular Response To Organic Substance Cell Death Death Chemical Homeostasis Cellular Homeostasis Regulation Of Cellular Process G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of MAPK Cascade Platelet Activation Homeostatic Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Signaling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Termination Of Signal Transduction	Membrane To Membrane Docking Cellular Extravasation Negative Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Transmembrane Transport Rho Protein Signal Transduction Negative Regulation Of Sodium Ion Transmembrane Transport Single Organismal Cell-cell Adhesion Cellular Chemical Homeostasis Cell Surface Receptor Signaling Pathway Membrane Docking Negative Regulation Of Ion Transport Negative Regulation Of Sodium Ion Transport Regulation Of Proton Transport Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Regulation Of Locomotion Cell Adhesion Cellular Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Cellular Component Organization Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Response To Organonitrogen Compound Regulation Of Transmembrane Transporter Activity Negative Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Blood Coagulation Hemostasis Regulation Of Excretion Chemical Homeostasis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Regulation Of Cell Shape Cell-matrix Adhesion Cellular Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Sodium Ion Transmembrane Transporter Activity Nervous System Development Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		18q 19p13 1q aberrations arising burkitt collaborating cooperate copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next profiling recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded	amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody
Tagcloud (Difference) ?		18q 19p13 1q aberrations arising burkitt collaborating cooperate copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next profiling recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded	amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody
Tagcloud (Intersection) ?