RIC8A and ZNF585B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RIC8A	ZNF585B
Gene Name		RIC8 guanine nucleotide exchange factor A	zinc finger protein 585B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nucleus
	Molecular Function	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding	Nucleic Acid Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	In Utero Embryonic Development Vasculature Development G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Visual Learning Cell Migration Involved In Gastrulation Positive Regulation Of GTPase Activity Cell-cell Adhesion Involved In Gastrulation Basement Membrane Organization	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Uterine fibroids ( 21460842)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		20 interactors: EFEMP1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS MAPK8IP3 NECAB2 NUTM1 RABAC1 SDCBP TERF1 TUBB2A UBQLN1 UBQLN4 XPO1 ZDHHC17 ZNF585B	1 interactors: RIC8A
Entrez ID		60626	92285
HPRD ID		12373	18354
Ensembl ID		ENSG00000177963	ENSG00000245680
Uniprot IDs		Q9NPQ8	Q52M93
PDB IDs
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Platelet Activation Blood Coagulation Hemostasis Dopamine Receptor Signaling Pathway Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Cyclase Activity Regulation Of Metabolic Process Signal Transduction Regulation Of CAMP Biosynthetic Process Cellular Response To Stimulus Regulation Of CAMP Metabolic Process Signaling Cell Communication Response To Stimulus Regulation Of Catalytic Activity Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Post-embryonic Development Regulation Of Cellular Process Negative Regulation Of CAMP Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Cell Division Response To Stress Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Response To Drug Regulation Of Phosphorus Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Catalytic Activity Vesicle Fusion Synaptic Transmission Post-embryonic Body Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Phospholipase Activity Organelle Fusion Positive Regulation Of Signal Transduction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Cellular Protein Metabolic Process Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity	Cell-cell Adhesion Involved In Gastrulation Cell Migration Involved In Gastrulation Basement Membrane Organization Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Visual Learning Visual Behavior Associative Learning Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Learning G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Ameboidal-type Cell Migration Gastrulation
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