RAD50 and MDC1

  • Number of citations of the paper that reports this interaction (PMID 12607005)
  • 193
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, unspecified method, pull down, affinity chromatography technology)

RAD50

MDC1

Gene Name RAD50 homolog (S. cerevisiae) mediator of DNA-damage checkpoint 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 8 interactors: DCLRE1C EP300 MDC1 MRE11A NBN RECQL5 RINT1 TERF2IP 37 interactors: ANAPC1 ATM BARD1 BRCA1 CASP3 CENPC CHEK2 COPS5 CREBBP CSNK2A1 DTX2 EP300 GATA4 H2AFX HDAC10 HDAC8 HINFP LOC729324 NBN NCL PIAS1 PIAS4 PRIM1 RAD50 RAD51 RNF8 SMC1A SUMO1 SUMO2 TP53 TP53BP1 UIMC1 USP28 VAMP5 WHSC1 WRN ZNF251
Entrez ID 10111 9656
HPRD ID 04950 16252
Ensembl ID ENSG00000113522 ENSG00000137337
Uniprot IDs A5D6Y3 Q92878 A1Z5I9 Q14676
PDB IDs 2ADO 2AZM 2ETX 3K05 3UEO 3UMZ 3UN0 3UNM 3UNN 3UOT
Enriched GO Terms of Interacting Partners?
Tagcloud ?
53bp1  applies  atr  coimmunoprecipitated  colocalized  combine  damaging  dda  ddas  dividing  dynein  etoposide  explaining  h2ax  interphase  microtubules  mre11  mta  mtas  nbs1  p63  p95  pk  sequestered  sequesters  slowly  synergize  traffic  vincristine 
53bp1  atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  h2ax  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Difference) ?
applies  atr  coimmunoprecipitated  colocalized  combine  damaging  dda  ddas  dividing  dynein  etoposide  explaining  interphase  microtubules  mre11  mta  mtas  nbs1  p63  p95  pk  sequestered  sequesters  slowly  synergize  traffic  vincristine 
atm  break  breaks  cajal  delays  dsb  dsbs  facilitates  facilitating  impairs  joining  localizes  neurodegeneration  nhej  nonhomologous  partner  premature  rad51  repair  rnf8  scaffold  strand  tcab1  ubiquitylation  wd40  wdr79  wrap53beta 
Tagcloud (Intersection) ?
53bp1  h2ax