RNF10 and EEF1A1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF10	EEF1A1
Gene Name		ring finger protein 10	eukaryotic translation elongation factor 1 alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autoubiquitination	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus
Pathways			HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Type 1 diabetes nephropathy ( 23028342)
Protein-Protein Interactions		28 interactors: CCDC90B COL4A5 EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A	123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1
Entrez ID		9921	1915
HPRD ID		11496	00559
Ensembl ID		ENSG00000022840	ENSG00000156508
Uniprot IDs		B3KWY9 Q8N5U6	P68104 Q6IPS9
PDB IDs			1SYW
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Negative Regulation Of Chromosome Organization Protein Metabolic Process Protein Monoubiquitination Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Catabolic Process Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Stress Proteolysis Regulation Of Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Phase Transition Toll-like Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Response To Oxygen Levels Mitotic Spindle Assembly Checkpoint Immune Response-regulating Signaling Pathway Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Transcription, DNA-templated Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Chromosome Segregation Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition	Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity
Tagcloud ?			akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?			akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?