RNF10 and CCDC90B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF10	CCDC90B
Gene Name		ring finger protein 10	coiled-coil domain containing 90B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrion Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transcription Regulatory Region DNA Binding
	Biological Process	Transcription, DNA-templated Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS		Type 1 diabetes nephropathy ( 23028342)
Protein-Protein Interactions		28 interactors: CCDC90B COL4A5 EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A	29 interactors: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 KDM1A LAMTOR1 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1
Entrez ID		9921	60492
HPRD ID		11496	14378
Ensembl ID		ENSG00000022840	ENSG00000137500
Uniprot IDs		B3KWY9 Q8N5U6	B3KP87 Q9GZT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Cellular Protein Modification Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Metabolic Process Negative Regulation Of Chromosome Organization Protein Metabolic Process Protein Monoubiquitination Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Catabolic Process Innate Immune Response Toll-like Receptor 4 Signaling Pathway Cellular Response To Stress Proteolysis Regulation Of Chromosome Organization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Cell Cycle Phase Transition Toll-like Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Cellular Response To Oxygen Levels Mitotic Spindle Assembly Checkpoint Immune Response-regulating Signaling Pathway Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Transcription, DNA-templated Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Chromosome Segregation Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of RNA Biosynthetic Process Activation Of Innate Immune Response Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition	Regulation Of Cell Proliferation Developmental Process System Development Anatomical Structure Development Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cellular Protein Metabolic Process Nucleoside Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleotide Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Multicellular Organismal Development Reactive Nitrogen Species Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Catalytic Activity Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Cell Differentiation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Inosine Catabolic Process Regulation Of Apoptosis Involved In Tissue Homeostasis Regulation Of Primitive Erythrocyte Differentiation Nicotinamide Riboside Catabolic Process Fetal Process Involved In Parturition Mitochondrial Electron Transport, Succinate To Ubiquinone NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Negative Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Membrane Tubulation Mucus Secretion Spermidine Acetylation Skeletal Muscle Cell Proliferation Interleukin-2 Secretion Urate Biosynthetic Process Purine Nucleoside Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Cellular Nitrogen Compound Metabolic Process Regulation Of Oxidoreductase Activity Endosome Localization Lung Goblet Cell Differentiation Protein-FAD Linkage Regulation Of Cholesterol Import Putrescine Catabolic Process Positive Regulation Of Skeletal Muscle Tissue Growth Response To Stimulus
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