SUMO2 and C18orf25

Number of citations of the paper that reports this interaction (PMID 16524884)
113

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		SUMO2	C18orf25
Gene Name		small ubiquitin-like modifier 2	chromosome 18 open reading frame 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm PML Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding
	Biological Process	Protein Sumoylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		91 interactors: ALAS1 ARL13A ARNTL ATXN1 ATXN7 AURKB BAD BCL11A BLM BRCC3 BRE C18orf25 CCNE2 CDCA8 CENPC CHAF1A CHD3 CMTM6 CORO2A CSNK2B CUL3 FAM175A FOS HDAC4 HDAC9 HIF1A HIPK2 HNF4A HOMEZ HSF2 JUN KALRN KDM1A KRT14 KRT5 KRT8 LEF1 MAF1 MAST2 MDC1 MSX1 MYB NFKBIA PARP1 PIAS1 PIAS2 PIAS3 PIAS4 PML RAC1 RANGAP1 RB1 RNF111 RNF4 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SH3KBP1 SLC22A2 SNCA SOX10 SOX6 SP100 STK24 SUMO1 TDG TDP2 TEAD3 TNIP1 TOPORS TP53BP2 TRIM63 UBA2 UBE2I USP25 USPL1 VIM WRN XPC ZBTB1 ZCCHC12 ZCCHC7 ZHX1 ZMYM2 ZMYM5	6 interactors: SRPK1 SRPK2 SUMO1 SUMO1P1 SUMO2 UBE2I
Entrez ID		6613	147339
HPRD ID		04332	12690
Ensembl ID		ENSG00000188612	ENSG00000152242
Uniprot IDs		P61956	Q5BIX2 Q96B23
PDB IDs		1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2RPQ 3UIN 3UIO
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Peptidyl-lysine Modification Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Binding RNA Metabolic Process Cellular Metabolic Process Gene Expression Chromosome Organization Organelle Organization Regulation Of DNA Binding Biosynthetic Process Response To Stimulus Regulation Of Cellular Process Cellular Response To Stimulus Negative Regulation Of Binding Protein Modification By Small Protein Conjugation Peptidyl-amino Acid Modification Regulation Of Cell Differentiation Regulation Of Signal Transduction Cellular Response To Stress	Protein Sumoylation Nucleus Organization Post-translational Protein Modification Positive Regulation Of Viral Genome Replication Peptidyl-lysine Modification Negative Regulation Of Viral Genome Replication Cellular Protein Modification Process Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Viral Genome Replication Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Viral Process Negative Regulation Of Viral Process Regulation Of MRNA Processing Protein Modification By Small Protein Conjugation Regulation Of RNA Splicing Nuclear Speck Organization Positive Regulation Of SUMO Transferase Activity Cellular Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Innate Immune Response Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Viral Process Peptidyl-amino Acid Modification Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process PML Body Organization Positive Regulation Of Protein Catabolic Process Chromosome Segregation Protein Localization To Nuclear Pore Protein Localization To Nuclear Envelope Organelle Organization Immune Response Positive Regulation Of Proteolysis Defense Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Sperm Chromatin Condensation Positive Regulation Of Metabolic Process RNA Splicing Regulation Of Protein Catabolic Process MRNA Processing Regulation Of Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma MRNA Metabolic Process Viral Process Regulation Of RNA Metabolic Process RNA Processing
Tagcloud ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Difference) ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief rev1 sensing short specialized starvation suppressor therapies toxic turn
Tagcloud (Intersection) ?