BCAR1 and FYB

Number of citations of the paper that reports this interaction (PMID 16020549)
3

Data Source:
HPRD (in vivo)

		BCAR1	FYB
Gene Name		breast cancer anti-estrogen resistance 1	FYN binding protein
Image
Gene Ontology Annotations	Cellular Component	Ruffle Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Lamellipodium	Nucleus Cytosol Actin Cytoskeleton
	Molecular Function	Signal Transducer Activity Protein Binding SH3 Domain Binding Protein Kinase Binding	Receptor Binding Protein Binding Protein Complex Binding
	Biological Process	Regulation Of Cell Growth Actin Filament Organization Cell Adhesion Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Integrin-mediated Signaling Pathway Blood Coagulation Cell Proliferation Insulin Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Cell Migration Platelet Activation Positive Regulation Of Cell Migration Cellular Response To Hepatocyte Growth Factor Stimulus Regulation Of Apoptotic Process Platelet-derived Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Hepatocyte Growth Factor Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Cell Division Cell Chemotaxis	Protein Phosphorylation NLS-bearing Protein Import Into Nucleus Immune Response Signal Transduction Biological_process Intracellular Signal Transduction T Cell Receptor Signaling Pathway
Pathways		Signaling by PDGF Signaling by VEGF Downstream signal transduction p130Cas linkage to MAPK signaling for integrins Integrin alphaIIb beta3 signaling Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) VEGFA-VEGFR2 Pathway	TCR signaling Generation of second messenger molecules Signal regulatory protein (SIRP) family interactions Adaptive Immune System
Drugs
Diseases
GWAS		Crohn's disease (time to surgery) ( 23665963)
Protein-Protein Interactions		52 interactors: ABL1 AJUBA ARHGAP32 BMX CASP3 CD2AP CRK CRKL CSPG4 DOCK1 E2F2 EFS ESR1 FES FXYD6 FYB FYN GRB2 GSN HCK HSPA5 INPPL1 LCK LYN MMP14 NCK1 NEDD9 NPHP1 PIK3R1 PKD1 PPAP2B PPP1R15A PTK2 PTK2B PTPN1 PTPN12 PTPRA PTPRF PTPRH PXN RAN RAPGEF1 SH2D3A SH2D3C SH3KBP1 SRC SRCIN1 TRIP6 TUBA4A UHRF2 VPS11 YWHAZ	14 interactors: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 SH2D1A SKAP1 SKAP2 SRC VASP WAS
Entrez ID		9564	2533
HPRD ID		04248	04107
Ensembl ID		ENSG00000050820	ENSG00000082074
Uniprot IDs		B2RBL9 B3KWE2 F5H855 P56945	O15117 Q05DE9
PDB IDs		1WYX 3T6G	1RI9 2GTJ 2GTO
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Signal Transduction Peptidyl-tyrosine Autophosphorylation Signaling Cell Communication Cellular Response To Stimulus Response To Stimulus Cell Migration Cell Motility Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Phosphorylation Platelet Activation Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Immune Response-activating Cell Surface Receptor Signaling Pathway Locomotion Cell Surface Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Response To Wounding ERBB Signaling Pathway Positive Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Wound Healing Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Cell Adhesion Regulation Of Cellular Component Organization Blood Coagulation Regulation Of Catalytic Activity Hemostasis Protein Autophosphorylation Positive Regulation Of Protein Metabolic Process Fc Receptor Signaling Pathway Innate Immune Response Response To Organonitrogen Compound Cellular Response To Organonitrogen Compound Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Phosphorylation Cellular Response To Peptide Hormone Stimulus Signal Complex Assembly Regulation Of Signaling	T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune Response Immune System Process Immune Response-regulating Signaling Pathway Regulation Of Immune Response Regulation Of Immune System Process Cell Surface Receptor Signaling Pathway Signaling Cell Communication Actin Filament Organization Signal Transduction Cell Activation Actin Polymerization Or Depolymerization Response To Stimulus Cellular Response To Stimulus Chemotaxis Actin Cytoskeleton Organization Actin Filament-based Process Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Immune Response Platelet Activation Leukocyte Activation Movement Of Cell Or Subcellular Component Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Body Fluid Levels Fc Receptor Signaling Pathway Response To Growth Factor Wound Healing Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Neuron Projection Morphogenesis Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To External Stimulus Response To Wounding Cell Morphogenesis Involved In Differentiation Locomotion Regulation Of Cellular Component Organization
Tagcloud ?		aldh1a1 anxa1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	agglutination alloantigens allotypic antigens antiglobulin arm coded delta disequilibria disequilibrium duffy existence fc fya granulocyte haplotype haplotypes hypothetical immunomodulatory immunophagocytosis indirect linkage lr na1 na2 phenotypes responder riia riiib
Tagcloud (Difference) ?		aldh1a1 anxa1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	agglutination alloantigens allotypic antigens antiglobulin arm coded delta disequilibria disequilibrium duffy existence fc fya granulocyte haplotype haplotypes hypothetical immunomodulatory immunophagocytosis indirect linkage lr na1 na2 phenotypes responder riia riiib
Tagcloud (Intersection) ?