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BCAR1 and PTPRH
Number of citations of the paper that reports this interaction (PMID
11278335
)
5
Data Source:
HPRD
(in vivo, in vitro)
BCAR1
PTPRH
Gene Name
breast cancer anti-estrogen resistance 1
protein tyrosine phosphatase, receptor type, H
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ruffle
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Actin Cytoskeleton
Lamellipodium
Cytoplasm
Integral Component Of Plasma Membrane
Molecular Function
Signal Transducer Activity
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Protein Binding
Biological Process
Regulation Of Cell Growth
Actin Filament Organization
Cell Adhesion
Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Blood Coagulation
Cell Proliferation
Insulin Receptor Signaling Pathway
Positive Regulation Of Endothelial Cell Migration
Cell Migration
Platelet Activation
Positive Regulation Of Cell Migration
Cellular Response To Hepatocyte Growth Factor Stimulus
Regulation Of Apoptotic Process
Platelet-derived Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Hepatocyte Growth Factor Receptor Signaling Pathway
Antigen Receptor-mediated Signaling Pathway
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Cell Division
Cell Chemotaxis
Protein Dephosphorylation
Apoptotic Process
Peptidyl-tyrosine Dephosphorylation
Pathways
Signaling by PDGF
Signaling by VEGF
Downstream signal transduction
p130Cas linkage to MAPK signaling for integrins
Integrin alphaIIb beta3 signaling
Platelet activation, signaling and aggregation
Platelet Aggregation (Plug Formation)
VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS
Crohn's disease (time to surgery) (
23665963
)
Protein-Protein Interactions
52 interactors:
ABL1
AJUBA
ARHGAP32
BMX
CASP3
CD2AP
CRK
CRKL
CSPG4
DOCK1
E2F2
EFS
ESR1
FES
FXYD6
FYB
FYN
GRB2
GSN
HCK
HSPA5
INPPL1
LCK
LYN
MMP14
NCK1
NEDD9
NPHP1
PIK3R1
PKD1
PPAP2B
PPP1R15A
PTK2
PTK2B
PTPN1
PTPN12
PTPRA
PTPRF
PTPRH
PXN
RAN
RAPGEF1
SH2D3A
SH2D3C
SH3KBP1
SRC
SRCIN1
TRIP6
TUBA4A
UHRF2
VPS11
YWHAZ
11 interactors:
BCAR1
DHPS
DOK1
GHR
KRTAP10-3
KRTAP10-8
LCK
MAPK1
MLH1
PTK2
PXN
Entrez ID
9564
5794
HPRD ID
04248
03942
Ensembl ID
ENSG00000050820
ENSG00000080031
Uniprot IDs
B2RBL9
B3KWE2
F5H855
P56945
C9JCH2
Q9HD43
PDB IDs
1WYX
3T6G
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Signaling
Cell Communication
Cellular Response To Stimulus
Response To Stimulus
Cell Migration
Cell Motility
Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Phosphorylation
Platelet Activation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Regulation Of Protein Phosphorylation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Locomotion
Cell Surface Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Response To Wounding
ERBB Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Wound Healing
Regulation Of Protein Kinase Activity
Regulation Of Signal Transduction
Cell Adhesion
Regulation Of Cellular Component Organization
Blood Coagulation
Regulation Of Catalytic Activity
Hemostasis
Protein Autophosphorylation
Positive Regulation Of Protein Metabolic Process
Fc Receptor Signaling Pathway
Innate Immune Response
Response To Organonitrogen Compound
Cellular Response To Organonitrogen Compound
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Cellular Response To Peptide Hormone Stimulus
Signal Complex Assembly
Regulation Of Signaling
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Peptide
Growth Hormone Receptor Signaling Pathway
Cellular Response To Growth Hormone Stimulus
Cellular Response To Hormone Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Growth Hormone
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Organonitrogen Compound
Enzyme Linked Receptor Protein Signaling Pathway
Response To Hormone
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Peptidyl-amino Acid Modification
B Cell Receptor Signaling Pathway
Platelet Activation
Cellular Response To Organic Substance
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Peptidyl-tyrosine Phosphorylation
Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Signal Complex Assembly
Response To Organic Substance
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Phosphorylation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of Protein Modification Process
Positive Regulation Of Immune System Process
Integrin-mediated Signaling Pathway
Blood Coagulation
Hemostasis
Antigen Receptor-mediated Signaling Pathway
Activation Of MAPK Activity
Immune Response-regulating Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
Regulation Of Protein Phosphorylation
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Kinase Activity
Insulin Receptor Signaling Pathway
Cellular Protein Modification Process
Positive Regulation Of Cellular Protein Metabolic Process
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Positive Regulation Of Transferase Activity
Tagcloud
?
aldh1a1
anxa1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
lox
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Intersection)
?