FYB and SKAP2

Number of citations of the paper that reports this interaction (PMID 9671755)
32

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		FYB	SKAP2
Gene Name		FYN binding protein	src kinase associated phosphoprotein 2
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Actin Cytoskeleton	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Receptor Binding Protein Binding Protein Complex Binding	SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Protein Phosphorylation NLS-bearing Protein Import Into Nucleus Immune Response Signal Transduction Biological_process Intracellular Signal Transduction T Cell Receptor Signaling Pathway	Protein Complex Assembly Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction B Cell Activation
Pathways		TCR signaling Generation of second messenger molecules Signal regulatory protein (SIRP) family interactions Adaptive Immune System	Signal regulatory protein (SIRP) family interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 SH2D1A SKAP1 SKAP2 SRC VASP WAS	11 interactors: APP FASLG FYB FYN HCK KHDRBS1 LYN PRAM1 PTK2B SRC TGFBR1
Entrez ID		2533	8935
HPRD ID		04107	05558
Ensembl ID		ENSG00000082074	ENSG00000005020
Uniprot IDs		O15117 Q05DE9	B7Z5N4 B7Z5R3 O75563
PDB IDs		1RI9 2GTJ 2GTO	3OMH
Enriched GO Terms of Interacting Partners?		T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune Response Immune System Process Immune Response-regulating Signaling Pathway Regulation Of Immune Response Regulation Of Immune System Process Cell Surface Receptor Signaling Pathway Signaling Cell Communication Actin Filament Organization Signal Transduction Cell Activation Actin Polymerization Or Depolymerization Response To Stimulus Cellular Response To Stimulus Chemotaxis Actin Cytoskeleton Organization Actin Filament-based Process Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Signal Transduction Blood Coagulation Hemostasis Immune Response Platelet Activation Leukocyte Activation Movement Of Cell Or Subcellular Component Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Body Fluid Levels Fc Receptor Signaling Pathway Response To Growth Factor Wound Healing Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Neuron Projection Morphogenesis Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To External Stimulus Response To Wounding Cell Morphogenesis Involved In Differentiation Locomotion Regulation Of Cellular Component Organization See more	Peptidyl-tyrosine Autophosphorylation Cell Surface Receptor Signaling Pathway Immune Response Protein Phosphorylation Immune System Process Protein Autophosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Immune Response-activating Cell Surface Receptor Signaling Pathway Phosphorylation Cell Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase Activity Locomotion Positive Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Signal Transduction Regulation Of Apoptotic Process Cell Migration Response To Lipid Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway Regulation Of Intracellular Transport Regulation Of Cell Death Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of Immune System Process Signaling Immune Response-regulating Signaling Pathway Peptidyl-amino Acid Modification Regulation Of Cell Projection Organization Cell Communication Regulation Of Extrinsic Apoptotic Signaling Pathway Platelet Activation Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Cellular Localization Regulation Of Signal Transduction Regulation Of Lipid Kinase Activity Cell Development Response To External Stimulus Leukocyte Migration Phosphate-containing Compound Metabolic Process Neuron Differentiation Wound Healing See more
Tagcloud ?		agglutination alloantigens allotypic antigens antiglobulin arm coded delta disequilibria disequilibrium duffy existence fc fya granulocyte haplotype haplotypes hypothetical immunomodulatory immunophagocytosis indirect linkage lr na1 na2 phenotypes responder riia riiib
Tagcloud (Difference) ?		agglutination alloantigens allotypic antigens antiglobulin arm coded delta disequilibria disequilibrium duffy existence fc fya granulocyte haplotype haplotypes hypothetical immunomodulatory immunophagocytosis indirect linkage lr na1 na2 phenotypes responder riia riiib
Tagcloud (Intersection) ?