FYB1

Description		FYN binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Protein-containing Complex Anchoring Junction
	Molecular Function	Signaling Receptor Binding Protein Binding Lipid Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway T Cell Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways		Generation of second messenger molecules Generation of second messenger molecules Signal regulatory protein family interactions
Drugs
Diseases
GWAS		Sleep (1/2-day periodicity) ( 33075057)
Interacting Genes		16 interacting genes: BCAR1 CBL CBLB ENAH EVL FASLG FYN LCP2 NCK2 SH2D1A SKAP1 SKAP2 SRC UBC VASP WAS
Entrez ID		2533
HPRD ID		04107
Ensembl ID		ENSG00000082074
Uniprot IDs		O15117
PDB IDs		1RI9 2GTJ 2GTO
Enriched GO Terms of Interacting Partners?		SH3 Domain Binding Actin Filament Organization Immune System Process Leukocyte Activation T Cell Receptor Signaling Pathway Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Profilin Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Supramolecular Fiber Organization Antigen Receptor-mediated Signaling Pathway Actin Polymerization Or Depolymerization Cytosol Immune Response-activating Signaling Pathway Cytoplasm Regulation Of Immune Response Phospholipase Binding Positive Regulation Of Protein-containing Complex Assembly Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of Cellular Component Organization Response To Platelet-derived Growth Factor Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Immune Response-regulating Signaling Pathway Activation Of Immune Response Focal Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Ephrin Receptor Binding Lymphocyte Activation Positive Regulation Of Cellular Component Organization Regulation Of Immune System Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Plasma Membrane Response To Growth Factor Regulation Of Actin Polymerization Or Depolymerization Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Actin Filament Length Phosphotyrosine Residue Binding Positive Regulation Of Actin Filament Polymerization Ephrin Receptor Signaling Pathway Regulation Of Leukocyte Cell-cell Adhesion Signal Complex Assembly Lamellipodium Receptor Tyrosine Kinase Binding Epidermal Growth Factor Receptor Signaling Pathway Cell-cell Junction Regulation Of Protein-containing Complex Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Signal Transduction
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