BCAR1 and HCK

  • Number of citations of the paper that reports this interaction (PMID 9020138)
  • 29
  • Data Source:
  • HPRD (in vitro)

BCAR1

HCK

Gene Name breast cancer anti-estrogen resistance 1 HCK proto-oncogene, Src family tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Crohn's disease (time to surgery) ( 23665963)
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 52 interactors: ABL1 AJUBA ARHGAP32 BMX CASP3 CD2AP CRK CRKL CSPG4 DOCK1 E2F2 EFS ESR1 FES FXYD6 FYB FYN GRB2 GSN HCK HSPA5 INPPL1 LCK LYN MMP14 NCK1 NEDD9 NPHP1 PIK3R1 PKD1 PPAP2B PPP1R15A PTK2 PTK2B PTPN1 PTPN12 PTPRA PTPRF PTPRH PXN RAN RAPGEF1 SH2D3A SH2D3C SH3KBP1 SRC SRCIN1 TRIP6 TUBA4A UHRF2 VPS11 YWHAZ 69 interactors: ABL1 ABL2 ACTB ADAM15 AGK APP ARRB1 ASAP1 BCAR1 BCR BTK C2orf44 CBL CCR3 CD2AP CHST15 CREBBP CSF2RB CSF3R CSK DNM2 DOK1 DOK2 ELMO1 ERBB3 EVL FASLG FCGR1A FCGR2A GOPC HNRNPK IL6ST INPP5D IRF2BPL KHDRBS1 KIT KRT40 KRTAP10-9 LCP2 MAP4K5 MTUS2 NOTCH2NL PAK2 PECAM1 PIK3CB PIK3R1 PIK3R2 PLAUR PLCG1 PLCG2 RAPGEF1 RASA1 RASA3 RPL10 SF3B3 SH3BP1 SH3KBP1 SKAP2 SOS1 SPRR2A STAT3 TNK2 TRPV4 TSG101 UNC119 VAV1 WAS WIPF1 WNT2
Entrez ID 9564 3055
HPRD ID 04248 00796
Ensembl ID ENSG00000050820 ENSG00000101336
Uniprot IDs B2RBL9 B3KWE2 F5H855 P56945 A8K4G3 P08631
PDB IDs 1WYX 3T6G 1AD5 1BU1 1QCF 2C0I 2C0O 2C0T 2HCK 2HK5 2OI3 2OJ2 3HCK 3NHN 3RBB 3REA 3REB 3VRY 3VRZ 3VS0 3VS1 3VS2 3VS3 3VS4 3VS5 3VS6 3VS7 4HCK 5HCK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aldh1a1  anxa1  cldn1  crmp1  endpoint  folr1  foxm1  il12rb2  il7r  inconclusive  kiaa1524  lox  mcm7  mta1  mtdh  ncoa3  ndrg2  nedd9  nes  overview  pbk  ppm1d  principally  prognostication  qualifying  slc7a5  sqstm1  warranted  wnt1 
32dcl3  32p  antisera  cbl  eliminated  engagement  fusion  fyn  gst  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Difference) ?
aldh1a1  anxa1  cldn1  crmp1  endpoint  folr1  foxm1  il12rb2  il7r  inconclusive  kiaa1524  lox  mcm7  mta1  mtdh  ncoa3  ndrg2  nedd9  nes  overview  pbk  ppm1d  principally  prognostication  qualifying  slc7a5  sqstm1  warranted  wnt1 
32dcl3  32p  antisera  cbl  eliminated  engagement  fusion  fyn  gst  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Intersection) ?