MINPP1 and ACTA1

Number of citations of the paper that reports this interaction (PMID 11536049)
0

Data Source:
HPRD (in vivo, in vitro)

		MINPP1	ACTA1
Gene Name		multiple inositol-polyphosphate phosphatase 1	actin, alpha 1, skeletal muscle
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Extracellular Vesicular Exosome	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Acid Phosphatase Activity Phosphohistidine Phosphatase Activity Bisphosphoglycerate 3-phosphatase Activity Inositol Hexakisphosphate 2-phosphatase Activity	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding
	Biological Process	Ossification Polyphosphate Metabolic Process Dephosphorylation Bone Mineralization Inositol Phosphate Metabolic Process Small Molecule Metabolic Process	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development
Pathways		Synthesis of IPs in the ER lumen Inositol phosphate metabolism	Striated Muscle Contraction
Drugs
Diseases
GWAS		Longevity ( 20304771)
Protein-Protein Interactions		3 interactors: ACTA1 SRF UBC	107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1
Entrez ID		9562	58
HPRD ID		05652	00030
Ensembl ID		ENSG00000107789	ENSG00000143632
Uniprot IDs		Q9UNW1	P68133 Q5T8M7
PDB IDs			1T44
Enriched GO Terms of Interacting Partners?		Myofibril Assembly Actomyosin Structure Organization Response To Abiotic Stimulus Contractile Actin Filament Bundle Assembly Striated Muscle Cell Development Muscle Cell Development Skeletal Muscle Fiber Adaptation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Striated Muscle Cell Differentiation Negative Regulation Of Beta-amyloid Clearance Response To Hypoxia Actin Filament Organization Striated Muscle Tissue Development Muscle Cell Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Muscle Tissue Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription By Glucose Regulation Of Beta-amyloid Clearance Skeletal Muscle Thin Filament Assembly Cardiac Vascular Smooth Muscle Cell Differentiation Regulation Of Transcription By Glucose Tangential Migration From The Subventricular Zone To The Olfactory Bulb Skeletal Myofibril Assembly Carbon Catabolite Regulation Of Transcription Skeletal Muscle Adaptation Dorsal Aorta Morphogenesis Response To Extracellular Stimulus Organelle Assembly Positive Thymic T Cell Selection Dorsal Aorta Development Response To Organic Substance Growth Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Viral Protein Processing Muscle Structure Development Primitive Streak Formation MRNA Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Cardiac Muscle Cell Myoblast Differentiation Stress Fiber Assembly Positive Regulation Of Transcription Via Serum Response Element Binding Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter MRNA Transcription Actin Cytoskeleton Organization Coronary Vasculature Development Cardioblast Differentiation Megakaryocyte Development Heart Trabecula Formation	Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly
Tagcloud ?		1pp 5pp dephosphorylate dephosphorylating diphosphoinositol enantio enantiomer enatiomer enigmatic hexakisphosphate ins insp5 insp6 insp7 ip6k ip6ks lumina metazoa n6 nitrobenzyl p5 pentakisphosphate phosphotransferase polyphosphate purine pyrophosphorylated sensitively tnp trifluorobenzyl	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		1pp 5pp dephosphorylate dephosphorylating diphosphoinositol enantio enantiomer enatiomer enigmatic hexakisphosphate ins insp5 insp6 insp7 ip6k ip6ks lumina metazoa n6 nitrobenzyl p5 pentakisphosphate phosphotransferase polyphosphate purine pyrophosphorylated sensitively tnp trifluorobenzyl	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?