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TRIM47 and UBE2U
Number of citations of the paper that reports this interaction (PMID
19690564
)
33
Data Source:
BioGRID
(two hybrid)
TRIM47
UBE2U
Gene Name
tripartite motif containing 47
ubiquitin-conjugating enzyme E2U (putative)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nuclear Chromatin
Cytoplasm
HULC Complex
Molecular Function
Zinc Ion Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
DNA Repair
Histone Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
White matter hyperintensity burden (
21681796
)
Protein-Protein Interactions
3 interactors:
APP
TRIM8
UBE2U
66 interactors:
ANAPC11
BARD1
BFAR
CADPS2
CGRRF1
DTX1
DZIP3
GOLGA2
KAT6A
MDM2
MIB1
MIB2
MID2
MKRN3
MUL1
PCGF1
PCGF2
PCGF6
PJA1
PML
RBCK1
RNF10
RNF11
RNF113A
RNF113B
RNF114
RNF125
RNF139
RNF14
RNF144B
RNF150
RNF166
RNF17
RNF170
RNF181
RNF2
RNF25
RNF26
RNF41
RNF5
RNFT1
SYVN1
TRAIP
TRIM15
TRIM2
TRIM23
TRIM24
TRIM27
TRIM28
TRIM3
TRIM32
TRIM34
TRIM35
TRIM37
TRIM38
TRIM46
TRIM47
TRIM5
TRIM54
TRIM63
TRIM65
TRIM68
TRIM74
VPS11
VPS41
ZSWIM2
Entrez ID
91107
148581
HPRD ID
15564
14599
Ensembl ID
ENSG00000132481
ENSG00000177414
Uniprot IDs
Q96AD0
Q96LD4
Q5VVX9
PDB IDs
1YRV
Enriched GO Terms of Interacting Partners
?
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axon Choice Point Recognition
Neuron Remodeling
Negative Regulation Of Viral Release From Host Cell
Protein Ubiquitination
Negative Regulation Of Viral Entry Into Host Cell
Protein Modification By Small Protein Conjugation
Cellular Copper Ion Homeostasis
Regulation Of Viral Entry Into Host Cell
Cellular Protein Modification Process
Negative Regulation Of Viral Transcription
Regulation Of Viral Release From Host Cell
Copper Ion Homeostasis
Suckling Behavior
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Response To Stress
Innate Immune Response
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Mating Behavior
Histone Ubiquitination
Endoplasmic Reticulum Calcium Ion Homeostasis
RNA Polyadenylation
Neuron Recognition
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Ionotropic Glutamate Receptor Signaling Pathway
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Cellular Protein Metabolic Process
Axon Cargo Transport
Mating
Neuromuscular Junction Development
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Cellular Protein Modification Process
Cellular Protein Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Protein Metabolic Process
Regulation Of Viral Release From Host Cell
Protein Polyubiquitination
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Process
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Process
Protein Catabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Autoubiquitination
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Innate Immune Response
Proteasomal Protein Catabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Cellular Macromolecule Catabolic Process
Regulation Of Protein Stability
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Gene Expression
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Histone H2A Monoubiquitination
Regulation Of Gene Expression
Histone H2A Ubiquitination
Histone H2A-K119 Monoubiquitination
Immune Response
Regulation Of Intracellular Transport
Cellular Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Defense Response
Interferon-gamma-mediated Signaling Pathway
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Histone Monoubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Viral Entry Into Host Cell
Response To Stress
Negative Regulation Of Viral Transcription
Regulation Of Apoptotic Process
Regulation Of RNA Metabolic Process
Cellular Response To Interferon-gamma
Protein Destabilization
Regulation Of Signal Transduction
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