TRIM47

Description		tripartite motif containing 47
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Postsynapse Glutamatergic Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination Regulation Of Postsynapse Assembly
Pathways
Drugs
Diseases
GWAS		Periventricular white matter hyperintensities ( 32517579) Psoriasis ( 28537254) Pulse pressure ( 30578418) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 21681796 25663218) White matter hyperintensity volume ( 29752348)
Interacting Genes		8 interacting genes: APP BLMH BRCA1 CYLD MRFAP1 TRIM8 UBE2D2 UBE2U
Entrez ID		91107
HPRD ID		15564
Ensembl ID		ENSG00000132481
Uniprot IDs		Q96LD4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Post-translational Protein Modification Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Modification Process Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Ubiquitin Conjugating Enzyme Activity Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Ubiquitin Protein Ligase Activity Protein Autoubiquitination Negative Regulation Of Interleukin-18-mediated Signaling Pathway Met1-linked Polyubiquitin Deubiquitinase Activity Canonical NF-kappaB Signal Transduction Regulation Of Apoptotic Signaling Pathway Acetylcholine Receptor Activator Activity Macromolecule Metabolic Process Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Protein Localization Cysteine-type Aminopeptidase Activity Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Regulation Of Non-canonical NF-kappaB Signal Transduction PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Mitotic Cell Cycle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Proteolysis Protein Linear Deubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Reactive Oxygen Species Metabolic Process Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response
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