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CCHCR1 and POLR2C
Number of citations of the paper that reports this interaction (PMID
16141233
)
6
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vitro, in vivo, two hybrid)
CCHCR1
POLR2C
Gene Name
coiled-coil alpha-helical rod protein 1
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Centriole
Nucleus
Nucleoplasm
DNA-directed RNA Polymerase II, Core Complex
Cytoplasm
Microtubule Cytoskeleton
Molecular Function
RNA Polymerase II Activity
DNA Binding
Protein Dimerization Activity
Biological Process
Protein Export From Nucleus
Multicellular Organismal Development
Cell Differentiation
MRNA Splicing, Via Spliceosome
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Gene Expression
Viral Process
PiRNA Metabolic Process
Somatic Stem Cell Maintenance
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
PIWI-interacting RNA (piRNA) biogenesis
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Regulatory RNA pathways
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Life Cycle
HIV Transcription Initiation
Influenza Viral RNA Transcription and Replication
RNA Pol II CTD phosphorylation and interaction with CE
Transcriptional regulation of pluripotent stem cells
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Transcriptional regulation by small RNAs
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
MicroRNA (miRNA) biogenesis
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription-coupled NER (TC-NER)
Viral Messenger RNA Synthesis
Formation of the HIV-1 Early Elongation Complex
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Hematology traits (
23263863
)
Nevirapine-induced rash (
21810746
)
Prostate cancer (
21743467
)
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) (
21912425
)
White blood cell count (
21738480
)
Protein-Protein Interactions
57 interactors:
ABI2
ALAS1
AMOTL2
ATG5
BLOC1S6
C1orf94
CARD9
CCDC102B
CCDC136
CCDC53
CDR2
CEP55
CTAGE5
DTNBP1
EFHC2
FSD2
GOLGA2
HAUS1
HSBP1
IKBKG
KRT13
KRT15
KRT31
KRT40
MAD1L1
MED4
MID2
MTUS2
NAB2
NDC80
NDEL1
NINL
NME7
NUP62
NUTM1
PIAS2
POLD2
POLR2C
PRKCG
RBM17
SAT1
SPAG5
SSX2IP
STAR
TADA2A
TEKT1
TFIP11
TPM3
TRAF1
TRAF2
TRAF4
TRIM27
TSGA10
TXLNA
TXLNB
USHBP1
ZFYVE19
26 interactors:
ATF4
ATF7IP
C11orf58
C14orf1
CCHCR1
EEF1A1
ITCH
LRIF1
MYOG
NEDD4
NFKBIA
NUDT21
POLR2A
POLR2B
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2J
POLR2K
POLR2L
SMARCC2
STC2
TAF15
UBE2W
Entrez ID
54535
5432
HPRD ID
05607
15945
Ensembl ID
ENSG00000204536
ENSG00000102978
Uniprot IDs
B0S7V6
D2IYK9
M1T2K8
M1TIV4
Q2TB68
Q769H0
Q8TD31
P19387
Q6FGR6
PDB IDs
Enriched GO Terms of Interacting Partners
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Mitotic Cell Cycle
Mitotic Cell Cycle Process
Microtubule-based Transport
Activation Of NF-kappaB-inducing Kinase Activity
Cytoskeleton-dependent Intracellular Transport
Organelle Organization
Positive Regulation Of NIK/NF-kappaB Signaling
Cell Cycle Process
NIK/NF-kappaB Signaling
Mitotic Nuclear Division
Cell Cycle
Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Microtubule-based Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Axon Cargo Transport
Innate Immune Response
Cell Division
Positive Regulation Of Protein Homodimerization Activity
Cytoskeleton Organization
Microtubule-based Movement
Establishment Of Organelle Localization
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Viral Transcription
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Viral Release From Host Cell
Establishment Of Vesicle Localization
Intracellular Receptor Signaling Pathway
Anterograde Synaptic Vesicle Transport
Negative Regulation Of Neuron Death
Vesicle Localization
Regulation Of Protein Homodimerization Activity
Centrosome Organization
Negative Regulation Of Viral Transcription
Melanosome Organization
Establishment Of Localization In Cell
Pigment Granule Organization
Regulation Of Viral Release From Host Cell
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Developmental Process
Organelle Localization
Microtubule Organizing Center Organization
Cellular Localization
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Anterograde Axon Cargo Transport
Regulation Of Apoptotic Process
Microtubule Cytoskeleton Organization
Positive Regulation Of JNK Cascade
Spindle Organization
Regulation Of Cell Death
7-methylguanosine MRNA Capping
PiRNA Metabolic Process
7-methylguanosine RNA Capping
Transcription Elongation From RNA Polymerase II Promoter
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
DNA-templated Transcription, Elongation
Somatic Stem Cell Maintenance
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Viral Process
Nucleotide-excision Repair
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
MRNA Splicing, Via Spliceosome
Stem Cell Maintenance
RNA Splicing, Via Transesterification Reactions
Regulation Of Viral Process
RNA Splicing
Transcription From RNA Polymerase II Promoter
Stem Cell Development
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
MRNA Processing
Transcription, DNA-templated
Positive Regulation Of Cellular Biosynthetic Process
Stem Cell Differentiation
RNA Biosynthetic Process
MRNA Metabolic Process
Cellular Response To Stress
Termination Of RNA Polymerase III Transcription
Transcription Elongation From RNA Polymerase III Promoter
RNA Processing
DNA Repair
Regulation Of Type I Interferon Production
NcRNA Metabolic Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Regulation Of Gene Expression
RNA Metabolic Process
Negative Regulation Of Cell Differentiation
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Termination
Regulation Of RNA Metabolic Process
Transcription From RNA Polymerase I Promoter
Positive Regulation Of Type I Interferon Production
DNA Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
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Tagcloud (Intersection)
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