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CCHCR1 and NUP62
Number of citations of the paper that reports this interaction (PubMedID
33961781
)
97
Data Source:
BioGRID
(two hybrid, affinity chromatography technology)
CCHCR1
NUP62
Description
coiled-coil alpha-helical rod protein 1
nucleoporin 62
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Centriole
Cytosol
Spindle Pole
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytoplasm
Centrosome
Cytoskeleton
Nuclear Membrane
Nuclear Pore Central Transport Channel
Mitotic Spindle
Flemming Body
Ribonucleoprotein Complex
Molecular Function
Protein Binding
Identical Protein Binding
Chromatin Binding
Protein Binding
Phospholipid Binding
Structural Constituent Of Nuclear Pore
Signaling Receptor Complex Adaptor Activity
Hsp70 Protein Binding
SH2 Domain Binding
Ubiquitin Binding
PTB Domain Binding
Hsp90 Protein Binding
Biological Process
Protein Export From Nucleus
Cell Differentiation
RNA Export From Nucleus
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Mitotic Metaphase Chromosome Alignment
Centrosome Cycle
Mitotic Centrosome Separation
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Protein Transport
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Canonical NF-kappaB Signal Transduction
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of DNA-templated Transcription
Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Centriole Replication
MRNA Transport
Regulation Of Mitotic Spindle Organization
Cellular Senescence
Centriole Assembly
Positive Regulation Of Mitotic Cytokinetic Process
Positive Regulation Of Protein Localization To Centrosome
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Feeling nervous (
29500382
)
Head and neck squamous cell carcinoma (
32276964
)
Hematology traits (
23263863
)
Hemoglobin (
32888494
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Malaria (
31844061
)
Mean spheric corpuscular volume (
32888494
)
Microalbuminuria (
31511532
)
Monocyte percentage of white cells (
32888494
)
Multiple myeloma (
23955597
)
Nevirapine-induced rash (
21810746
)
Night sleep phenotypes (
27126917
)
Prostate cancer (
21743467
)
Psoriasis (
30921485
)
Reticulocyte count (
32888494
)
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) (
21912425
)
Ulcerative colitis (
28067908
)
Urinary albumin-to-creatinine ratio (
31511532
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
White blood cell count (
21738480
)
Interacting Genes
161 interacting genes:
ABI1
ABI2
AIRIM
ALAS1
AMOTL2
ANKRD11
ATG5
BFSP1
BICD2
BLOC1S2
BLOC1S6
C1orf94
CARD9
CBY2
CCDC102B
CCDC13
CCDC136
CCDC197
CCDC33
CCDC88B
CCNC
CDC37
CDR2
CDR2L
CDSN
CEP55
CEP57
CEP63
CFAP53
CIMIP4
CNN1
CNOT2
CRACR2A
CTAG1A
CTAG1B
DEUP1
DISC1
DMAP1
DRC4
DTNB
DYDC1
EFHC2
EXOC4
EXOC7
EXOC8
FSD2
GLRX3
GNG13
GOLGA2
GOLGA6L9
GRAP2
HAUS1
HAUS8
HDDC3
HGFAC
HOMEZ
HOOK2
HSF2BP
HSPB1
IFT20
IKBKG
IKZF3
ING5
KIAA0753
KIFC3
KRT13
KRT15
KRT16
KRT18
KRT19
KRT24
KRT27
KRT31
KRT34
KRT35
KRT36
KRT75
LENG1
LHX8
LZTS1
MAD1L1
MBD3
MCRS1
MED4
MIA2
MID2
MTUS2
NAB2
NDC80
NFKBID
NINL
NME7
NTAQ1
NUP54
NUP62
NUTM1
OIP5
PCM1
PFDN6
PIAS2
PIBF1
PKP2
PLEKHA7
POLD2
POLR2C
POU6F2
PPP1R13B
PRDM6
PRKCG
PROSER3
RABGEF1
RALBP1
RBM17
RBM41
RCOR3
RINT1
RUSC1
SAMD11
SAT1
SMARCE1
SORBS3
SPAG5
SPG21
SSX2IP
STAR
STARD4
STMN2
STX11
SYCE1
SYCE1L
TACC3
TADA2A
TEKT1
TEX9
TFIP11
TPM1
TPM3
TRAF1
TRAF2
TRAF4
TRIM27
TRIM54
TRIML2
TSG101
TSGA10
TSHZ3
TXLNA
TXLNB
USHBP1
VPS52
VPS9D1
WASHC3
ZBTB16
ZFYVE19
ZGPAT
ZNF620
ZNF629
ZNF655
ZNF774
ZRANB1
ZWINT
88 interacting genes:
ABI2
ADAM15
AGR3
ARFIP2
ATF7IP2
ATXN7
BFSP1
BLOC1S6
C14orf119
C1orf216
CAVIN3
CCDC121
CCDC146
CCDC150
CCHCR1
CENPU
CEP57L1
CLIC1
CRCT1
DDX3X
DGCR6
DPPA3
DRC12
DTNB
DYNLT1
FABP3
GOPC
GORASP2
GTF2E2
HAUS1
HGS
HSF2
HSF4
IDH1
IFT20
IFT25
IK
IKBIP
IPO5
ISCU
KANSL1
KIFC3
KLHL32
KPNA1
KPNA2
KPNB1
KRT1
KRT20
KRT3
KRT6A
KRT6B
KRT75
LMO2
LNX1
MUC1
MXD3
MYO15B
NUP153
NUP54
NUP58
NUP98
NUTF2
NXF1
NXF2
OGT
OIP5
OTUD6A
PBX2
PELI2
PIN1
PTMA
RANBP2
SMARCA2
SMARCE1
SNAPC5
SP1
SSC5D
SUOX
THAP1
TLE4
TRAF3
TRIML2
TXLNA
TXN
USHBP1
WASHC3
XPO1
XPO6
Entrez ID
54535
23636
HPRD ID
05607
05782
Ensembl ID
ENSG00000204536
ENSG00000213024
Uniprot IDs
A0A1U9X7G6
B0S7V6
B4DIA2
D2IYK9
M1T2K8
M1TIV4
Q2TB68
Q769H0
Q8TD31
P37198
PDB IDs
5IJN
5IJO
7PER
7R5J
7R5K
Enriched GO Terms of Interacting Partners
?
Cytoskeleton
Cytoskeleton Organization
Supramolecular Fiber Organization
Microtubule-based Process
Centrosome
Protein Binding
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Intermediate Filament Organization
Organelle Organization
Structural Constituent Of Skin Epidermis
Centriolar Satellite
Keratin Filament
Intermediate Filament
Structural Molecule Activity
Cytoplasm
Spindle Pole
Cytoskeleton-dependent Intracellular Transport
Organelle Localization
Microtubule Organizing Center Organization
Microtubule
Microtubule-based Transport
Microtubule Cytoskeleton Organization
Cytosol
Flemming Body
Transport Along Microtubule
Microtubule-based Movement
Organelle Assembly
Protein Localization To Centrosome
Identical Protein Binding
Microtubule Binding
Centrosome Cycle
Protein Localization To Cytoskeleton
Signaling Adaptor Activity
Establishment Of Localization In Cell
Intracellular Transport
Cell Division
Centriole
Regulation Of Microtubule Cytoskeleton Organization
Epithelial Cell Differentiation
Cellular Localization
Microtubule Organizing Center
Cilium Assembly
Ciliary Basal Body
Structural Constituent Of Cytoskeleton
Establishment Of Organelle Localization
Vesicle Tethering Involved In Exocytosis
Axonemal A Tubule Inner Sheath
Thioesterase Binding
Syntaxin Binding
Nuclear Transport
Nucleocytoplasmic Transport
Nuclear Localization Sequence Binding
Nuclear Pore
NLS-bearing Protein Import Into Nucleus
RNA Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Export
MRNA Transport
Intracellular Transport
Nuclear Import Signal Receptor Activity
Protein Localization To Nucleus
Protein Transport
Establishment Of Protein Localization
Structural Constituent Of Nuclear Pore
Intermediate Filament Organization
Nuclear Membrane
Nucleobase-containing Compound Transport
Nuclear Inclusion Body
Protein Binding
Intermediate Filament Cytoskeleton Organization
Structural Constituent Of Skin Epidermis
Intermediate Filament-based Process
Intracellular Protein Transport
Cellular Localization
Protein Localization To Organelle
Establishment Of Localization In Cell
Establishment Of Protein Localization To Organelle
Supramolecular Fiber Organization
Nuclear Envelope
Intracellular Protein Localization
Intracellular Transport Of Virus
Keratin Filament
Host Cell
NLS-dependent Protein Nuclear Import Complex
Cytoskeleton Organization
Small GTPase Binding
Intermediate Filament
Protein Export From Nucleus
Keratinization
Nuclear Pore Nuclear Basket
Regulation Of Nucleocytoplasmic Transport
Nuclear Pore Organization
Identical Protein Binding
RNA Export From Nucleus
Nucleus Organization
Organelle Organization
Ribosomal Protein Import Into Nucleus
Viral Penetration Into Host Nucleus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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