VAV1 and SIAH2

  • Number of citations of the paper that reports this interaction (PMID 10207103)
  • 14
  • Data Source:
  • BioGRID (two hybrid, pull down, affinity chromatography technology)
  • HPRD (in vitro, in vivo, two hybrid)

VAV1

SIAH2

Gene Name vav 1 guanine nucleotide exchange factor siah E3 ubiquitin protein ligase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 77 interactors: ABL1 ACTA1 AOC3 ARHGDIA ARHGDIB BCR BLNK BTK CASP3 CBL CBLB CD19 CDC42 CRK CXCR4 DNM2 DOCK2 DOK1 EGFR EMD EPOR ERBB2 ERBB3 EZH2 FGFR1 FYN GRB2 HCK HNRNPK HRAS IL6ST INSR JAK2 JUN KHDRBS1 LAT LCK LCP2 LMNA MAPK1 MERTK MET NEK3 PAG1 PDGFRB PHAX PIK3R1 PLCG1 PRKCQ PRLR PTK2B PTPN22 PTPN6 RAC1 RACGAP1 RAF1 RHOA RHOG S100B SH3BP2 SHB SHC1 SIAH1 SIAH2 SLA SOCS1 SYK TEC TUBA1A TUBA4A TUBB TYK2 XRCC5 XRCC6 ZAP70 ZNF655 ZYX 39 interactors: AFF1 ATN1 CACYBP CCBE1 DCC DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 OPRM1 PEG10 PEG3 PIAS1 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 USP13 USP19 VAV1
Entrez ID 7409 6478
HPRD ID 01284 03737
Ensembl ID ENSG00000141968 ENSG00000181788
Uniprot IDs B2R8B5 P15498 Q96D37 O43255
PDB IDs 2CRH 2LCT 2MC1 2ROR 3BJI 3KY9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  silenced  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
adding  complexity  decisions  determines  e3  fail  fate  favoring  feedback  finger  hipk2  homeodomain  inactivated  interferes  ligase  loop  preferentially  proline  stimulates  switch  termination  ubiquitin  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
Tagcloud (Difference) ?
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  silenced  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
adding  complexity  decisions  determines  e3  fail  fate  favoring  feedback  finger  hipk2  homeodomain  inactivated  interferes  ligase  loop  preferentially  proline  stimulates  switch  termination  ubiquitin  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
Tagcloud (Intersection) ?