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PPFIA2 and GIT1
Number of citations of the paper that reports this interaction (PMID
12629171
)
40
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
PPFIA2
GIT1
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
G protein-coupled receptor kinase interacting ArfGAP 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cell Surface
Presynaptic Active Zone
Extracellular Vesicular Exosome
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Aggresome
Molecular Function
Protein Binding
Protein Complex Binding
Protein Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Biological Process
Cell-matrix Adhesion
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Axon Guidance
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of ARF GTPase Activity
Regulation Of Cytokinesis
Positive Regulation Of GTPase Activity
Ephrin Receptor Signaling Pathway
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Ephrin signaling
Axon guidance
EPH-Ephrin signaling
Drugs
Diseases
GWAS
Schizophrenia (
22885689
)
Protein-Protein Interactions
13 interactors:
CAST
CDC5L
ERC2
GIT1
ITSN1
PPFIA1
PPFIA3
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
50 interactors:
ADRBK1
ADRBK2
ARHGEF6
ARHGEF7
BARD1
C8orf33
CCDC113
CENPU
CHD3
DDX24
EIF6
GIT2
GRB2
GRK5
GRK6
HAP1
HMOX2
HTT
KIAA1377
KIF1A
LAMTOR5
LRIF1
MAN2A2
NEK2
PAK3
PCLO
PDPK1
PFDN1
PLCG1
PMF1
PPFIA1
PPFIA2
PPFIA3
PPFIA4
PTK2
PTPRZ1
PXN
RAN
RGS2
RIF1
SDCCAG3
SRC
SRRT
TAB1
TERF1
TGFB1I1
TRIB3
TXNDC9
WDR33
YWHAG
Entrez ID
8499
28964
HPRD ID
04392
06577
Ensembl ID
ENSG00000139220
ENSG00000108262
Uniprot IDs
G3V200
O75334
Q59FC3
Q9Y2X7
PDB IDs
3TAC
3TAD
Enriched GO Terms of Interacting Partners
?
Peptidyl-tyrosine Dephosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Protein Dephosphorylation
Signaling
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Communication
Dephosphorylation
Signal Transduction
Glutamate Secretion
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Stimulus
Acid Secretion
Dicarboxylic Acid Transport
Ephrin Receptor Signaling Pathway
Neurotransmitter Secretion
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Regulation Of Neurotransmitter Levels
Synaptic Transmission
Nervous System Development
Amino Acid Transport
Neurotransmitter Transport
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Receptor Binding
Presynaptic Membrane Assembly
Generation Of Neurons
Negative Regulation Of Stress Fiber Assembly
Presynaptic Membrane Organization
Neurogenesis
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Cellular Process
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cell-cell Signaling
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cellular Response To Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Response To Growth Factor
Regulation Of Signal Transduction
Regulation Of Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Organonitrogen Compound
Cell Cycle
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Regulation Of Intracellular Signal Transduction
Termination Of Signal Transduction
Glutamate Secretion
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Signal Complex Assembly
Regulation Of Neurotransmitter Levels
Cellular Response To Organic Substance
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Dicarboxylic Acid Transport
Fibroblast Growth Factor Receptor Signaling Pathway
Neurotransmitter Transport
Fc Receptor Signaling Pathway
Positive Regulation Of Catalytic Activity
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of Protein Kinase Activity
Cell Projection Organization
Regulation Of Catalytic Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Neurotransmitter Secretion
Regulation Of Kinase Activity
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Positive Regulation Of Metabolic Process
Cell-substrate Adhesion
Regulation Of Apoptotic Process
Response To Organonitrogen Compound
Regulation Of Phosphorus Metabolic Process
Response To Peptide
Positive Regulation Of Signal Transduction
Signaling
Acid Secretion
Negative Regulation Of Signal Transduction
Regulation Of Phosphorylation
Tagcloud
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git2
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Difference)
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git2
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Intersection)
?