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PPFIA2 and PPFIA1
Number of citations of the paper that reports this interaction (PMID
9624153
)
49
Data Source:
HPRD
(in vivo, in vitro)
PPFIA2
PPFIA1
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cell Surface
Presynaptic Active Zone
Extracellular Vesicular Exosome
Cytoplasm
Cytosol
Focal Adhesion
Presynaptic Active Zone
Molecular Function
Protein Binding
Protein Complex Binding
Signal Transducer Activity
Protein Binding
Biological Process
Cell-matrix Adhesion
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Cell-matrix Adhesion
Signal Transduction
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Schizophrenia (
22885689
)
Protein-Protein Interactions
13 interactors:
CAST
CDC5L
ERC2
GIT1
ITSN1
PPFIA1
PPFIA3
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
25 interactors:
AGTPBP1
CAST
CCNH
CEP70
DTNB
ERC1
ERC2
FAM161A
GIT1
MBIP
NCOA2
NDN
PPFIA2
PPFIA3
PPFIBP1
PPFIBP2
PPP2R5D
PTPRC
PTPRD
PTPRF
PTPRG
PTPRS
TNNT1
TXLNA
YWHAG
Entrez ID
8499
8500
HPRD ID
04392
11451
Ensembl ID
ENSG00000139220
ENSG00000131626
Uniprot IDs
G3V200
O75334
B3KVS8
Q13136
PDB IDs
3TAC
3TAD
Enriched GO Terms of Interacting Partners
?
Peptidyl-tyrosine Dephosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Protein Dephosphorylation
Signaling
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Communication
Dephosphorylation
Signal Transduction
Glutamate Secretion
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Stimulus
Acid Secretion
Dicarboxylic Acid Transport
Ephrin Receptor Signaling Pathway
Neurotransmitter Secretion
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Regulation Of Neurotransmitter Levels
Synaptic Transmission
Nervous System Development
Amino Acid Transport
Neurotransmitter Transport
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Receptor Binding
Presynaptic Membrane Assembly
Generation Of Neurons
Negative Regulation Of Stress Fiber Assembly
Presynaptic Membrane Organization
Neurogenesis
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Cellular Process
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cell-cell Signaling
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Dephosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Signaling
Cell Communication
Cell Cycle Phase Transition
Nervous System Development
G2/M Transition Of Mitotic Cell Cycle
Glutamate Secretion
Cellular Protein Modification Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Transcription Initiation From RNA Polymerase I Promoter
Generation Of Neurons
Transcription From RNA Polymerase I Promoter
Neurogenesis
Cell Adhesion
Signal Transduction
Negative Regulation Of Protein Kinase Activity
Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway
Negative Regulation Of Kinase Activity
Acid Secretion
Mitotic Cell Cycle Phase Transition
Cellular Response To Stimulus
Immunoglobulin Biosynthetic Process
Positive Regulation Of Hematopoietic Stem Cell Migration
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transferase Activity
Phosphate-containing Compound Metabolic Process
Dicarboxylic Acid Transport
DNA-templated Transcription, Elongation
Cellular Protein Metabolic Process
Negative Regulation Of Protein Phosphorylation
Neuron Differentiation
C-terminal Protein Deglutamylation
Regulation Of Catalytic Activity
Regulation Of Protein Kinase Activity
Response To Stimulus
Neurotransmitter Secretion
Cell Surface Receptor Signaling Pathway
Developmental Process
Histone Acetylation
Negative Regulation Of Catalytic Activity
Cerebellum Development
Regulation Of Kinase Activity
Negative Regulation Of Phosphorylation
Tagcloud
?
11q13
aberrations
acgh
aiming
amplicon
apart
band
breakpoints
candidates
ccnd1
chosen
chr
comprised
copies
cttn
distinguish
fadd
gain
homogeneously
laryngeal
microarray
oncogene
oncogenes
oraov1
q13
rearrangements
reinvestigated
sevenfold
ways
Tagcloud (Difference)
?
11q13
aberrations
acgh
aiming
amplicon
apart
band
breakpoints
candidates
ccnd1
chosen
chr
comprised
copies
cttn
distinguish
fadd
gain
homogeneously
laryngeal
microarray
oncogene
oncogenes
oraov1
q13
rearrangements
reinvestigated
sevenfold
ways
Tagcloud (Intersection)
?