PPFIA2 and PTPRF

Number of citations of the paper that reports this interaction (PMID 9624153)
49

Data Source:
HPRD (in vivo, in vitro)

		PPFIA2	PTPRF
Gene Name		protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	protein tyrosine phosphatase, receptor type, F
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cell Surface Presynaptic Active Zone Extracellular Vesicular Exosome	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Complex Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Heparin Binding Protein Complex Binding
	Biological Process	Cell-matrix Adhesion Synaptic Transmission Neurotransmitter Secretion Glutamate Secretion	Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Migration Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Receptor Binding
Pathways		Dopamine Neurotransmitter Release Cycle Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Serotonin Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Schizophrenia ( 22885689)	Amyotrophic lateral sclerosis (age of onset) ( 22959728)
Protein-Protein Interactions		13 interactors: CAST CDC5L ERC2 GIT1 ITSN1 PPFIA1 PPFIA3 PPFIBP1 PPFIBP2 PTPRD PTPRF PTPRG PTPRS	23 interactors: BCAR1 CAV1 CDH1 CTNNB1 FRS2 FYN GALNT1 INSR IRS1 IRS2 JUP LCK NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RET SKIL TRIO ZNF512B
Entrez ID		8499	5792
HPRD ID		04392	01552
Ensembl ID		ENSG00000139220	ENSG00000142949
Uniprot IDs		G3V200 O75334	P10586
PDB IDs		3TAC 3TAD	1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Dephosphorylation Enzyme Linked Receptor Protein Signaling Pathway Protein Dephosphorylation Signaling Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Communication Dephosphorylation Signal Transduction Glutamate Secretion Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Stimulus Acid Secretion Dicarboxylic Acid Transport Ephrin Receptor Signaling Pathway Neurotransmitter Secretion Cell Surface Receptor Signaling Pathway Response To Stimulus Regulation Of Neurotransmitter Levels Synaptic Transmission Nervous System Development Amino Acid Transport Neurotransmitter Transport Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Receptor Binding Presynaptic Membrane Assembly Generation Of Neurons Negative Regulation Of Stress Fiber Assembly Presynaptic Membrane Organization Neurogenesis Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Cellular Process Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Cell-cell Signaling	Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Growth Factor Stimulus Response To Organonitrogen Compound Response To Growth Factor Cellular Response To Organic Substance Response To Peptide Hormone Response To Peptide Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Hormone Stimulus Cell Adhesion Insulin Receptor Signaling Pathway Response To Hormone Cellular Response To Indole-3-methanol Epidermal Growth Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Apoptotic Process Cellular Response To Insulin Stimulus Signaling Regulation Of Cell Death System Development Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Communication Locomotion Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Cellular Component Movement Phosphatidylinositol-mediated Signaling Positive Regulation Of Glycogen Biosynthetic Process Response To Insulin Multicellular Organismal Development Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Anatomical Structure Development Organ Development Cell Migration Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Cell Motility Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Signal Transduction
Tagcloud ?			1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold
Tagcloud (Difference) ?			1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold
Tagcloud (Intersection) ?