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PPFIA2 and PTPRD
Number of citations of the paper that reports this interaction (PMID
9624153
)
49
Data Source:
HPRD
(in vitro)
PPFIA2
PTPRD
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
protein tyrosine phosphatase, receptor type, D
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cell Surface
Presynaptic Active Zone
Extracellular Vesicular Exosome
Integral Component Of Plasma Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Protein Complex Binding
Transmembrane Receptor Protein Tyrosine Phosphatase Activity
Receptor Binding
Protein Binding
Cell Adhesion Molecule Binding
Biological Process
Cell-matrix Adhesion
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Protein Dephosphorylation
Phosphate-containing Compound Metabolic Process
Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Neuron Differentiation
Peptidyl-tyrosine Dephosphorylation
Positive Regulation Of Dendrite Morphogenesis
Presynaptic Membrane Assembly
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Schizophrenia (
22885689
)
Airflow obstruction (
22837378
)
Attention deficit hyperactivity disorder and conduct disorder (
18951430
)
Myopia (pathological) (
23049088
)
Obesity-related traits (
23251661
)
Palmitic acid (16:0) plasma levels (
23362303
)
Partial epilepsies (
20522523
)
Platelet aggregation (
20526338
)
Restless legs syndrome (
18660810
21779176
)
Temperament (
22832960
)
Type 2 diabetes (
21647700
20174558
)
Protein-Protein Interactions
13 interactors:
CAST
CDC5L
ERC2
GIT1
ITSN1
PPFIA1
PPFIA3
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
8 interactors:
MTSS1
PPFIA1
PPFIA2
PPFIA3
PTPRA
PTPRE
PTPRF
PTPRS
Entrez ID
8499
5789
HPRD ID
04392
03358
Ensembl ID
ENSG00000139220
ENSG00000153707
Uniprot IDs
G3V200
O75334
F5GWT7
P23468
Q2HXI4
Q3KPI9
Q59H90
PDB IDs
3TAC
3TAD
1X5Z
2DLH
2YD6
2YD7
Enriched GO Terms of Interacting Partners
?
Peptidyl-tyrosine Dephosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Protein Dephosphorylation
Signaling
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Communication
Dephosphorylation
Signal Transduction
Glutamate Secretion
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Stimulus
Acid Secretion
Dicarboxylic Acid Transport
Ephrin Receptor Signaling Pathway
Neurotransmitter Secretion
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Regulation Of Neurotransmitter Levels
Synaptic Transmission
Nervous System Development
Amino Acid Transport
Neurotransmitter Transport
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Receptor Binding
Presynaptic Membrane Assembly
Generation Of Neurons
Negative Regulation Of Stress Fiber Assembly
Presynaptic Membrane Organization
Neurogenesis
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Cellular Process
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cell-cell Signaling
Glutamate Secretion
Peptidyl-tyrosine Dephosphorylation
Protein Dephosphorylation
Acid Secretion
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Dicarboxylic Acid Transport
Neurotransmitter Secretion
Dephosphorylation
Regulation Of Neurotransmitter Levels
Signaling
Cell Communication
Cell Adhesion
Amino Acid Transport
Neurotransmitter Transport
Carboxylic Acid Transport
Organic Acid Transport
Enzyme Linked Receptor Protein Signaling Pathway
Organic Anion Transport
Secretion By Cell
Adherens Junction Maintenance
Synaptic Transmission
Secretion
Anion Transport
Cell-matrix Adhesion
Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Nephron Tubule Epithelial Cell Differentiation
Microspike Assembly
Signal Transduction
Cell-substrate Adhesion
Negative Regulation Of Receptor Binding
Cell-cell Signaling
Negative Regulation Of Stress Fiber Assembly
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Magnesium Ion Homeostasis
Corpus Callosum Development
Cellular Response To Fluid Shear Stress
Glomerulus Morphogenesis
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of Protein Localization To Plasma Membrane
Cellular Response To Stimulus
Regulation Of Actin Filament-based Process
Cellular Component Maintenance
Phosphate-containing Compound Metabolic Process
Movement Of Cell Or Subcellular Component
Regulation Of Cytoskeleton Organization
Regulation Of Mast Cell Activation
Response To Fluid Shear Stress
Negative Regulation Of Insulin Receptor Signaling Pathway
Tagcloud
?
alignment
atlas
bayesian
brip1
bssv
calculate
called
coverage
enables
evident
false
framework
integrating
lowered
paired
pgr
precision
rad51
rank
read
shared
simulated
simultaneous
somatic
ssv
ssvs
subtracting
svs
tools
Tagcloud (Difference)
?
alignment
atlas
bayesian
brip1
bssv
calculate
called
coverage
enables
evident
false
framework
integrating
lowered
paired
pgr
precision
rad51
rank
read
shared
simulated
simultaneous
somatic
ssv
ssvs
subtracting
svs
tools
Tagcloud (Intersection)
?