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PPFIA2 and ERC2
Number of citations of the paper that reports this interaction (PMID
12923177
)
33
Data Source:
HPRD
(two hybrid, in vitro, in vivo)
PPFIA2
ERC2
Gene Name
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
ELKS/RAB6-interacting/CAST family member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Cell Surface
Presynaptic Active Zone
Extracellular Vesicular Exosome
Cytoplasm
Cytoskeleton
Cell Junction
Growth Cone
Presynaptic Membrane
Presynaptic Active Zone
Molecular Function
Protein Binding
Protein Complex Binding
Protein Binding
Biological Process
Cell-matrix Adhesion
Synaptic Transmission
Neurotransmitter Secretion
Glutamate Secretion
Pathways
Dopamine Neurotransmitter Release Cycle
Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
Serotonin Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Schizophrenia (
22885689
)
Bipolar disorder and schizophrenia (
21057379
)
Hip geometry (
17903296
)
Protein-Protein Interactions
13 interactors:
CAST
CDC5L
ERC2
GIT1
ITSN1
PPFIA1
PPFIA3
PPFIBP1
PPFIBP2
PTPRD
PTPRF
PTPRG
PTPRS
8 interactors:
BSN
MYB
PCLO
PPFIA1
PPFIA2
PPFIA3
PPFIA4
RIMS1
Entrez ID
8499
26059
HPRD ID
04392
10810
Ensembl ID
ENSG00000139220
ENSG00000187672
Uniprot IDs
G3V200
O75334
O15083
PDB IDs
3TAC
3TAD
Enriched GO Terms of Interacting Partners
?
Peptidyl-tyrosine Dephosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Protein Dephosphorylation
Signaling
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Cell Communication
Dephosphorylation
Signal Transduction
Glutamate Secretion
Cell Adhesion
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cellular Response To Stimulus
Acid Secretion
Dicarboxylic Acid Transport
Ephrin Receptor Signaling Pathway
Neurotransmitter Secretion
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Regulation Of Neurotransmitter Levels
Synaptic Transmission
Nervous System Development
Amino Acid Transport
Neurotransmitter Transport
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Receptor Binding
Presynaptic Membrane Assembly
Generation Of Neurons
Negative Regulation Of Stress Fiber Assembly
Presynaptic Membrane Organization
Neurogenesis
Negative Regulation Of Actin Filament Bundle Assembly
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Cellular Process
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Cell-cell Signaling
Glutamate Secretion
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Neurotransmitter Transport
Acid Secretion
Dicarboxylic Acid Transport
Synaptic Transmission
Amino Acid Transport
Cell-cell Signaling
Secretion By Cell
Secretion
Carboxylic Acid Transport
Organic Acid Transport
Organic Anion Transport
Anion Transport
Ion Transport
Establishment Of Localization In Cell
Cellular Localization
Transport
Synaptic Vesicle Exocytosis
Regulation Of Neuronal Synaptic Plasticity
Signaling
Cell Communication
Synaptic Vesicle Transport
Regulation Of Synaptic Plasticity
Cell-matrix Adhesion
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Establishment Of Vesicle Localization
Vesicle Localization
Cell-substrate Adhesion
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Negative Regulation Of Stress Fiber Assembly
Regulation Of Cellular Localization
Negative Regulation Of Actin Filament Bundle Assembly
Positive Regulation Of Histone H3-K9 Methylation
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Synaptic Transmission
Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane
Establishment Of Organelle Localization
Exocytosis
Positive Regulation Of Histone H3-K4 Methylation
Negative Regulation Of Protein Localization To Plasma Membrane
CAMP-mediated Signaling
Regulation Of Histone H3-K4 Methylation
Organelle Localization
Cellular Response To Interleukin-6
Positive Regulation Of T-helper Cell Differentiation
Cyclic-nucleotide-mediated Signaling
Regulation Of Long-term Neuronal Synaptic Plasticity
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Tagcloud (Difference)
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Tagcloud (Intersection)
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