Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
PLEKHN1 and TP53BP2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PLEKHN1
TP53BP2
Gene Name
pleckstrin homology domain containing, family N member 1
tumor protein p53 binding protein 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Nucleus
Cytoplasm
Perinuclear Region Of Cytoplasm
Molecular Function
SH3/SH2 Adaptor Activity
Protein Binding
SH3 Domain Binding
Identical Protein Binding
NF-kappaB Binding
Biological Process
Cell Cycle
Signal Transduction
Central Nervous System Development
Heart Development
Embryo Development Ending In Birth Or Egg Hatching
Positive Regulation Of Signal Transduction
Response To Ionizing Radiation
Negative Regulation Of Cell Cycle
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
LPXN
LZTS2
REL
RFX6
SPERT
TAX1BP1
TCF4
TP53BP2
TRAF1
TRIM27
58 interactors:
APP
ATPAF2
ATXN7
BAIAP2
BCL2
BCL2L1
CCDC92
CSNK2B
CWF19L2
DCUN1D1
EEF1A1
GRB2
HIST1H2BC
HNRNPUL1
KIF5A
LMO4
MAGI1
MAPK8IP2
MRPL20
MTMR14
NAE1
NDC80
NUTM1
OTUB2
PLEKHN1
PLK1
POLR2L
PPHLN1
PPP1CA
PPP1CB
PPP1CC
PRKAB2
PRPF31
PTN
RELA
SIAH1
SIAH2
SSX2IP
SUMO2
SUMO3
TANK
TBC1D22B
TCL1A
TP53
TRAF4
TXLNA
UBASH3A
UNC119
USP4
UTP14A
WWP1
WWP2
YAP1
YES1
YWHAG
YWHAQ
ZGPAT
ZNF26
Entrez ID
84069
7159
HPRD ID
13190
11803
Ensembl ID
ENSG00000187583
ENSG00000143514
Uniprot IDs
Q494U1
Q13625
PDB IDs
1YCS
2UWQ
4A63
Enriched GO Terms of Interacting Partners
?
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Regulation Of Protein Localization
Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Component Assembly
Regulation Of Protein Secretion
Protein Complex Assembly
Regulation Of Cellular Localization
Regulation Of Gene Expression
Pancreatic D Cell Differentiation
Pancreatic Epsilon Cell Differentiation
Regulation Of Nitrogen Compound Metabolic Process
Pancreas Development
Signal Transduction
Transcription, DNA-templated
Negative Regulation Of Interleukin-2 Secretion
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Cytokine Production
RNA Biosynthetic Process
Signaling
Cell Communication
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Cytokine Production
Response To Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Transport
Regulation Of Secretion
Maintenance Of DNA Repeat Elements
Regulation Of Establishment Of Protein Localization
Regulation Of Cell Death
Regulation Of Cellular Process
Negative Regulation Of Calcium Ion Import
Negative Regulation Of B Cell Receptor Signaling Pathway
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Insulin Secretion
Embryonic Genitalia Morphogenesis
Cellular Response To Stimulus
Glucose Homeostasis
Negative Regulation Of Cytokine Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Neuron Death
Neuron Apoptotic Process
Response To Radiation
Regulation Of Signal Transduction
Regulation Of Signaling
Response To External Stimulus
Negative Regulation Of Signal Transduction
Entrainment Of Circadian Clock By Photoperiod
Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Negative Regulation Of Signaling
Photoperiodism
Entrainment Of Circadian Clock
Positive Regulation Of Apoptotic Signaling Pathway
Cell Part Morphogenesis
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Metabolic Process
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Phosphorylation
Response To Light Stimulus
Protein Modification By Small Protein Conjugation
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cell Cycle
Neuron Projection Morphogenesis
Regulation Of Mitochondrion Organization
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cell Projection Morphogenesis
Axonogenesis
Cellular Protein Modification Process
Positive Regulation Of Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Cell Morphogenesis
Regulation Of Protein Metabolic Process
Cell Morphogenesis Involved In Differentiation
Regulation Of Cellular Protein Metabolic Process
Response To Gamma Radiation
Axon Development
Regulation Of Extrinsic Apoptotic Signaling Pathway
Mitotic Cell Cycle
Generation Of Neurons
Nervous System Development
Cellular Response To Ionizing Radiation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Mitochondrion Organization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Innate Immune Response
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Neuron Projection Development
Neurogenesis
Anatomical Structure Morphogenesis
Tagcloud
?
adenovirus
angiotensin
apoptosis
array
at2r
bag3
bmp6
bmp7
bnipi
cytokine
downregulation
du145
gadd45a
hrk
il6
il8
mapk
microrna
next
numerous
p44
pc
r2
silence
sirnas
tnfsf10
trail
transduced
utilized
Tagcloud (Difference)
?
adenovirus
angiotensin
apoptosis
array
at2r
bag3
bmp6
bmp7
bnipi
cytokine
downregulation
du145
gadd45a
hrk
il6
il8
mapk
microrna
next
numerous
p44
pc
r2
silence
sirnas
tnfsf10
trail
transduced
utilized
Tagcloud (Intersection)
?