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PLEKHN1 and TRAF1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
PLEKHN1
TRAF1
Gene Name
pleckstrin homology domain containing, family N member 1
TNF receptor-associated factor 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Cytoplasm
Molecular Function
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Biological Process
Protein Complex Assembly
Apoptotic Process
Signal Transduction
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Celiac disease and Rheumatoid arthritis (
21383967
)
Rheumatoid arthritis (
20453842
19503088
)
Protein-Protein Interactions
10 interactors:
LPXN
LZTS2
REL
RFX6
SPERT
TAX1BP1
TCF4
TP53BP2
TRAF1
TRIM27
164 interactors:
A1CF
ACTN3
AES
AKAP17A
ALS2CR11
AQP1
ARNT2
ARSJ
BARD1
BCL6
BEX2
BIRC2
BIRC3
C14orf105
C19orf66
C1orf109
C1orf216
C5orf30
CARHSP1
CASP10
CASP3
CASP6
CASP8
CCDC116
CCDC120
CCDC146
CCHCR1
CD40
CDCA3
CDKN1A
CDKN2B
CFLAR
CHCHD3
COX5B
CRYGA
CYB5R2
DEPTOR
DGCR6
DMRT3
DOK3
ECH1
EDAR
EHHADH
EWSR1
FAM161A
FAM86C1
FBF1
FBXL18
FOSL2
GATA2
GATAD2B
GEM
GFI1B
GIT2
GLRX3
GMCL1P1
GNG5
GORASP2
HAUS1
HEY2
HIVEP3
HOXA1
HOXD12
IKBKB
JOSD1
KIAA1217
KIF1A
KLHL38
KPNA2
LATS1
LCOR
LOC149950
LTBR
MAP3K14
MAP6
MAPRE2
METTL17
MORN3
MOS
MYEF2
NEBL
NGFRAP1
NUFIP2
NUPL1
OLIG3
PBX3
PDE4D
PHF21A
PIN1
PKN1
PLEKHN1
POM121L4P
POP5
PPP1R13B
PRDM7
PSMA1
PSMB1
QRICH1
RASAL2
RASSF5
RBCK1
RBM41
RBM45
RIPK1
RIPK2
RNF31
RTP5
SCNM1
SIK3
SLC25A48
SLC25A6
SNW1
SPG21
SPOP
SRC
SSC5D
STK3
SYCE1
TANK
TBC1D16
TCL1A
TEAD4
TFAP4
THAP7
TICAM1
TNFAIP3
TNFRSF11A
TNFRSF12A
TNFRSF14
TNFRSF17
TNFRSF18
TNFRSF19
TNFRSF1A
TNFRSF1B
TNFRSF4
TNFRSF8
TNFRSF9
TNFSF9
TRADD
TRAF2
TRAF3IP2
TRAF6
TRAIP
TRIM23
TRIM37
TRIM42
TRPV6
TSSC4
USP7
WAC
ZC2HC1C
ZFYVE21
ZFYVE26
ZNF124
ZNF20
ZNF417
ZNF440
ZNF502
ZNF512B
ZNF564
ZNF572
ZNF581
ZNF587
ZNF662
Entrez ID
84069
7185
HPRD ID
13190
03418
Ensembl ID
ENSG00000187583
ENSG00000056558
Uniprot IDs
Q494U1
Q13077
PDB IDs
3M0D
Enriched GO Terms of Interacting Partners
?
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Regulation Of Protein Localization
Regulation Of Signal Transduction
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Component Assembly
Regulation Of Protein Secretion
Protein Complex Assembly
Regulation Of Cellular Localization
Regulation Of Gene Expression
Pancreatic D Cell Differentiation
Pancreatic Epsilon Cell Differentiation
Regulation Of Nitrogen Compound Metabolic Process
Pancreas Development
Signal Transduction
Transcription, DNA-templated
Negative Regulation Of Interleukin-2 Secretion
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Cytokine Production
RNA Biosynthetic Process
Signaling
Cell Communication
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Cytokine Production
Response To Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Transport
Regulation Of Secretion
Maintenance Of DNA Repeat Elements
Regulation Of Establishment Of Protein Localization
Regulation Of Cell Death
Regulation Of Cellular Process
Negative Regulation Of Calcium Ion Import
Negative Regulation Of B Cell Receptor Signaling Pathway
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Insulin Secretion
Embryonic Genitalia Morphogenesis
Cellular Response To Stimulus
Glucose Homeostasis
Negative Regulation Of Cytokine Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cell Death
Death
Programmed Cell Death
Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Apoptotic Process
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of Cell Death
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of NF-kappaB Transcription Factor Activity
Response To Tumor Necrosis Factor
Regulation Of Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
Intracellular Signal Transduction
Positive Regulation Of Cell Death
Regulation Of Metabolic Process
Positive Regulation Of Apoptotic Process
Regulation Of Cellular Process
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Cellular Response To Tumor Necrosis Factor
Regulation Of Necroptotic Process
Regulation Of Transcription, DNA-templated
Immune System Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of RNA Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Signal Transduction
Regulation Of RNA Biosynthetic Process
Toll-like Receptor 4 Signaling Pathway
Regulation Of Gene Expression
Regulation Of Intracellular Signal Transduction
Regulation Of Signal Transduction
Positive Regulation Of Cellular Metabolic Process
Signaling
Immune Response-regulating Signaling Pathway
Regulation Of Cytokine Production
Cell Communication
Pattern Recognition Receptor Signaling Pathway
Positive Regulation Of Immune System Process
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Protein Modification Process
Tagcloud
?
adaptor
appear
characterization
convey
daxx
death
domains
effector
fadd
far
growing
homologies
insights
isolation
jun
mammalian
members
mort
necrosis
represents
rip
seem
share
signals
superfamily
tnfr
tradd
transmit
Tagcloud (Difference)
?
adaptor
appear
characterization
convey
daxx
death
domains
effector
fadd
far
growing
homologies
insights
isolation
jun
mammalian
members
mort
necrosis
represents
rip
seem
share
signals
superfamily
tnfr
tradd
transmit
Tagcloud (Intersection)
?