PLEKHN1 and PIH1D1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHN1	PIH1D1
Description		pleckstrin homology domain containing N1	PIH1 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Mitochondrial Membrane	Nucleus Nucleolus Cytoplasm Pre-snoRNP Complex R2TP Complex RPAP3/R2TP/prefoldin-like Complex Ribonucleoprotein Complex
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidic Acid Binding Cardiolipin Binding Phosphatidylinositol Phosphate Binding	RNA Polymerase I Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Protein Kinase Binding Histone Binding ATPase Binding Phosphoprotein Binding Histone Reader Activity
	Biological Process	Response To Hypoxia Positive Regulation Of Apoptotic Process 3'-UTR-mediated MRNA Destabilization	Box C/D SnoRNP Assembly Chromatin Remodeling RRNA Processing Epithelial Cell Differentiation SnoRNA Localization Protein Stabilization Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of TORC2 Signaling Positive Regulation Of TORC1 Signaling TORC1 Complex Assembly
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Parkinson's disease ( 26227905)
Interacting Genes		42 interacting genes: ABI2 AKAP8L ARID5A ATXN1 CBY2 CYSRT1 FHL5 HOXA1 KRT31 KRT36 KRT83 KRTAP1-3 KRTAP19-6 KRTAP6-2 LPXN LZTS2 MTUS2 NBPF19 NFKBID NOTCH2NLA PDLIM7 PIH1D1 PPM1J PPP1R16B PRICKLE4 PRKAA2 REL RFX6 SAXO4 SORBS3 SSC4D TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27 TRIP6 USP54 WWOX ZC4H2 ZNF438 ZRANB1	19 interacting genes: BYSL CA4 CDCA7L EAF1 FAM90A1 FARP1 GEM MAPK6 MFAP1 MISP PLEKHN1 RBPMS RCOR3 SCNM1 SEPTIN1 SMARCD1 TNS4 TSC22D4 UBC
Entrez ID		84069	55011
HPRD ID		13190	07938
Ensembl ID		ENSG00000187583	ENSG00000104872
Uniprot IDs		Q494U1	Q9NWS0
PDB IDs			4PSF 4PSI 6GXZ 7AVC 8BDU
Enriched GO Terms of Interacting Partners?		Intermediate Filament Structural Constituent Of Skin Epidermis Keratin Filament
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