CASP6 and TOP1

  • Number of citations of the paper that reports this interaction (PMID 9933635)
  • 19
  • Data Source:
  • HPRD (in vitro)

CASP6

TOP1

Gene Name caspase 6, apoptosis-related cysteine peptidase topoisomerase (DNA) I
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: APP CASP10 CASP3 CASP8 CFLAR CHD3 COPS6 DSP EIF2S1 HTT IKBKG KRT18 LMNA LMNB1 MAPK6 MAPT NEDD4 NUAK1 PCYT1A PIN1 PPL PRKAB2 PRKCZ PSEN1 PSEN2 PSME3 RB1 SATB1 SP1 SRF SRP72 TAB1 TFAP2A TOP1 TRAF1 UBE4A UBE4B VIM 55 interactors: APAF1 APP ATM BARD1 BTBD1 BTBD2 BUB3 CASP3 CASP6 CDK8 CKAP5 CSNK2A1 CSNK2A2 DDB2 ELK3 ERCC8 ERG FSHR GEMIN4 GRWD1 IL7R IRF4 IRF8 IRF9 JAK1 JUN KMT2A LIG4 LSM4 MDM2 NCL NCOA6 PDE10A PPP2R2B PRB1 PYGM RBL1 RBL2 RCVRN SF3B1 SFPQ SNRNP70 SNW1 SRSF1 SRSF11 SUMO1 SYMPK TARBP2 TDP1 TOPORS TP53 TRIM32 TUBD1 U2AF2 UBE2I
Entrez ID 839 7150
HPRD ID 03321 00535
Ensembl ID ENSG00000138794 ENSG00000198900
Uniprot IDs P55212 P11387
PDB IDs 1MI9 2WDP 3K7E 3NKF 3NR2 3OD5 3P45 3P4U 3QNW 3S70 3S8E 3V6L 3V6M 4EJF 4FXO 4HVA 1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5fu  aacr  abrogating  antimetastatic  arrests  chemoresistance  chemoresponse  default  dissemination  disseminative  drivers  filament  hallmark  hemidesmosomal  itraq  junctions  phosphorylations  phosphorylative  prometastatic  proteomics  reinstate  repressing  res  s25  s38  stathmin  stmn1  tethering  twin 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Difference) ?
5fu  aacr  abrogating  antimetastatic  arrests  chemoresistance  chemoresponse  default  dissemination  disseminative  drivers  filament  hallmark  hemidesmosomal  itraq  junctions  phosphorylations  phosphorylative  prometastatic  proteomics  reinstate  repressing  res  s25  s38  stathmin  stmn1  tethering  twin 
anucleate  catalytically  complements  dispensable  division  evolutionarily  homologs  hypersensitive  inviability  inviable  lethal  mitosis  permissive  pombe  probable  proper  restrictive  schizosaccharomyces  searches  semi  synthetically  thiabendazole  top1p  topoisomerase  trf4  trf4p  trf5  trf5p  ts 
Tagcloud (Intersection) ?