CASP6 and PSEN2

  • Number of citations of the paper that reports this interaction (PMID 9219695)
  • 38
  • Data Source:
  • HPRD (in vivo, in vitro)

CASP6

PSEN2

Gene Name caspase 6, apoptosis-related cysteine peptidase presenilin 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 38 interactors: APP CASP10 CASP3 CASP8 CFLAR CHD3 COPS6 DSP EIF2S1 HTT IKBKG KRT18 LMNA LMNB1 MAPK6 MAPT NEDD4 NUAK1 PCYT1A PIN1 PPL PRKAB2 PRKCZ PSEN1 PSEN2 PSME3 RB1 SATB1 SP1 SRF SRP72 TAB1 TFAP2A TOP1 TRAF1 UBE4A UBE4B VIM 58 interactors: AAMP ACTG1 APH1A APH1B APP BCL2L1 CAPN1 CASP1 CASP3 CASP6 CASP7 CASP8 CEP55 CFLAR CHKA CIB1 CSNK1A1 CSNK1D CSNK2A1 CTNNB1 CTNND2 DNAJB1 DOCK3 ECD EID1 ELAVL1 EVI5L EXOC6 FBXL12 FHL2 FLNA FLNB GCDH GFAP HPS1 ICAM5 IFIT3 IFIT5 KCNIP3 KCNIP4 LIPF MAST1 METTL2B MGEA5 NCSTN NOS3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PDCD4 PSENEN RAB11A RHEB RNF32 SPC24 SRI UBQLN1
Entrez ID 839 5664
HPRD ID 03321 02860
Ensembl ID ENSG00000138794 ENSG00000143801
Uniprot IDs P55212 P49810
PDB IDs 1MI9 2WDP 3K7E 3NKF 3NR2 3OD5 3P45 3P4U 3QNW 3S70 3S8E 3V6L 3V6M 4EJF 4FXO 4HVA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
5fu  aacr  abrogating  antimetastatic  arrests  chemoresistance  chemoresponse  default  dissemination  disseminative  drivers  filament  hallmark  hemidesmosomal  itraq  junctions  phosphorylations  phosphorylative  prometastatic  proteomics  reinstate  repressing  res  s25  s38  stathmin  stmn1  tethering  twin 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hallmark  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Difference) ?
5fu  aacr  abrogating  antimetastatic  arrests  chemoresistance  chemoresponse  default  dissemination  disseminative  drivers  filament  hemidesmosomal  itraq  junctions  phosphorylations  phosphorylative  prometastatic  proteomics  reinstate  repressing  res  s25  s38  stathmin  stmn1  tethering  twin 
abeta1  accelerated  amyloid  apoe4  bace1  becomes  casp3  deposits  event  hyperphosphorylation  increasingly  later  losses  nonetheless  nonsynonymous  nontransgenic  oxys  picalm  posits  precede  proof  psen1  snps  sorl1  sporadic  triggers  turn  unlikely 
Tagcloud (Intersection) ?
hallmark