CEP63 and FBF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP63	FBF1
Gene Name		centrosomal protein 63kDa	Fas (TNFRSF6) binding factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Centriole Cytosol	Spindle Pole Centrosome Centriole Cytosol Apical Junction Complex Keratin Filament Ciliary Transition Fiber
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division	Organelle Organization Cilium Assembly Apical Junction Assembly Establishment Of Epithelial Cell Polarity
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Height ( 18391952)
Protein-Protein Interactions		44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10	48 interactors: ABI3 ACCS AES APP BLZF1 CALCOCO2 CCDC102B CCDC67 CCDC85B CEP55 CEP63 CINP DGCR6 FAM208B FAS GATA1 GCC1 GOLGA2 HIF1AN IFT20 IKZF3 KRT13 KRT31 KRT40 LZTS2 MEOX2 MID2 MIPOL1 PNMA1 RBPMS RHOXF2 SSX2IP SUMO1 TADA2A TCEA2 TEX11 TMCC2 TRAF1 TRAF2 TRIM23 TRIM27 TRIM29 TRIM54 TSGA10 TTC32 TUBGCP4 USHBP1 VPS37B
Entrez ID		80254	85302
HPRD ID		07826	10948
Ensembl ID		ENSG00000182923	ENSG00000188878
Uniprot IDs		Q96MT8	J3KPL7 Q8TES7
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process	Regulation Of Binding Cellular Component Assembly Negative Regulation Of Binding Microtubule-based Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Protein Binding Regulation Of RNA Metabolic Process Neuron Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Mitotic Cell Cycle Centriole Assembly Negative Regulation Of Viral Release From Host Cell Cell Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Signal Transduction Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Regulation Of Transcription From RNA Polymerase II Promoter Organelle Assembly Transcription, DNA-templated Regulation Of Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Immune Response Negative Regulation Of Gene Expression Organelle Organization Protein Complex Assembly Protein K63-linked Ubiquitination Negative Regulation Of Biosynthetic Process Microtubule-based Transport RNA Biosynthetic Process Positive Regulation Of Proteolysis Protein Trimerization Intraciliary Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Localization Peptidyl-histidine Hydroxylation Peptidyl-asparagine Hydroxylation Opsin Transport Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Peptidase Activity Innate Immune Response Negative Regulation Of Nucleic Acid-templated Transcription Protein Localization To Golgi Apparatus
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